Toxoplasma pneumonitis: fatal presentation of disseminated toxoplasmosis in a patient with AIDS.

Toxoplasma pneumonitis: fatal presentation of disseminated toxoplasmosis in a patient with AIDS.
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弓形虫肺炎:艾滋病患者传播性弓形虫病的致命表现。

DOI:
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发表时间:
1992
影响因子:
24.3
通讯作者:
Fiona Mulcahy
Fiona Mulcahy
中科院分区:
医学1区
文献类型:
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作者:
C. Bergin;M. Murphy;D. Lyons;E. Gaffney;Fiona Mulcahy

文献摘要

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弓形虫感染是获得性免疫缺陷综合征 (AIDS) 患者肺炎的罕见原因。我们报告了一例致命性肺弓形虫病,其临床症状类似于卡氏肺孢子虫肺炎(PCP)。弓形体病的传统诊断方法缺乏敏感性。支气管镜检查和经支气管活检标本的组织学评估未能识别感染微生物。尸检发现有播散性感染的证据。
Toxoplasma gondii infection is an uncommon cause of pneumonitis in patients with acquired immune deficiency syndrome (AIDS). We report a case of fatal pulmonary toxoplasmosis, which clinically resembled Pneumocystis carinii pneumonia (PCP). Conventional diagnostic methods for toxoplasmosis lack sensitivity. Bronchoscopy and histological evaluation of transbronchial biopsy specimens failed to identify the infecting organism. At autopsy there was evidence of disseminated infection.