Piezoelectric tactile sensor for submucosal tumor detection in endoscopy

Piezoelectric tactile sensor for submucosal tumor detection in endoscopy
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DOI:
10.1016/j.sna.2016.04.020
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发表时间:
2016-06-15
影响因子:
4.6
通讯作者:
Teng, Ying-Juimr
Teng, Ying-Juimr
中科院分区:
工程技术3区
文献类型:
--
作者:
Chuang, Cheng-Hsin;Li, Tsan-Hsiu;Teng, Ying-Juimr

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在这项研究中,我们已经制造了一个小型化的压电触觉传感器(空集= 1.4毫米),是适合安装在内窥镜检测粘膜下肿瘤。传感机制基于串联弹簧模型,由两个刚度不同的部件组成,即嵌入软外包装中的硬内部结构。PVDF传感膜的电压输出与每个组件施加的局部法向应力成比例,并且该差分输出可用于提取关于测试对象/生物组织的弹性的信息。传感器的设计已经过测试,通过嵌入不同的弹性体和人工肿瘤在猪的胃中模拟人类粘膜下肿瘤的条件,并显示出良好的协议与理论分析和数值模拟。传感器响应在1.01-3.51 MPa的范围内与测试样品的杨氏模量成比例,使其适用于检测软组织中存在的肿瘤。所提出的小型化触觉传感器利用无源感测元件,通过可以插入内窥镜通道的金属导管连接到外部读出系统,由于其具有生物相容性包装,因此可以安全地插入胃中,并且因此可以用于在常规内窥镜检查期间提供触觉信息。(C)© 2016 Elsevier B. V.版权所有。
In this study, we have fabricated a miniaturized piezoelectric tactile sensor (empty set = 1.4 mm) that is suitable for mounting on an endoscope to detect submucosal tumors. The sensing mechanism is based on a tandem spring model and consists of two components with varying stiffness, namely a hard inner structure embedded in a soft outer packaging. The voltage output of the PVDF sensing film is proportional to the localized normal stress exerted by each component and this differential output can be used to extract information about the elasticity of the test object/biological tissue. The sensor design has been tested by embedding different elastomers and artificial tumors in a pig's stomach for simulating the conditions of submucosal tumors in humans and shows good agreement with theoretical analysis and numerical simulations. The sensor response is proportional to the Young's modulus of test sample over a range of 1.01-3.51 MPa, making it suitable for detection of tumors present in soft tissues. The proposed miniaturized tactile sensor utilizes a passive sensing element, is wired to the external readout system through the metal catheter which can be inserted into the endoscopic channel, is safe for insertion into the stomach as it has a biocompatible packaging and can thus be utilized to provide tactile information during regular endoscopy. (C) 2016 Elsevier B.V. All rights reserved.