INHIBITION OF AXON REFLEX VASODILATATION BY TOPICALLY APPLIED CAPSAICIN
INHIBITION OF AXON REFLEX VASODILATATION BY TOPICALLY APPLIED CAPSAICIN
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DOI：
10.1111/1523-1747.ep12520912
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发表时间：
1981-01-01
影响因子：
6.5
通讯作者：
LORINCZ, AL
中科院分区：
文献类型：
--
作者：
BERNSTEIN, JE;SWIFT, RM;LORINCZ, AL
辣椒素局部应用于人体皮肤产生了最初的烧灼反应，在24小时内减少，使皮肤对组胺诱导的轴突反射血管舒张无反应，而不改变对疼痛，触觉和温度的敏感性。从局部感觉神经末梢的P物质的耗尽可以解释这种辣椒素效应。
Topical application of capsaicin to human skin produced an initial burning erythematous reaction, which diminished over 24 h leaving the skin unresponsive to histamine-induced axon reflex vasodilatation without altering sensitivity to pain, touch and temperature. Depletion of substance P from local sensory nerve terminals may explain this capsaicin effect.