Observations from the CDC - Preventing alcohol-exposed pregnancies among women of childbearing age: The necessity of a preconceptional approach
Observations from the CDC - Preventing alcohol-exposed pregnancies among women of childbearing age: The necessity of a preconceptional approach
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DOI：
10.1089/152460999319048
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发表时间：
1999-07-01
期刊：
影响因子：
--
通讯作者：
Boyle, CA
中科院分区：
文献类型：
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作者：
Floyd, RL;Ebrahim, SH;Boyle, CA
在美国，胎儿酒精综合征(FAS)被认为是导致智力低下的主要可预防原因之一。1虽然Fas主要是在母亲在怀孕期间长期大量饮酒的儿童中发现的，2正在进行的研究记录了产前酒精暴露造成的一系列不利生殖、婴儿和儿童健康后果，其中一些开始的阈值低至每周四杯。3、4虽然调查显示，10名妇女中有9名知道怀孕期间饮酒对生殖健康造成不利影响，1 1995年，大约175 000名怀孕妇女暴露在已知的酒精水平下，从而增加了不良妊娠和婴儿结局的风险。5.孕期酒精暴露的不良影响在整个孕期都有，但在怀孕初期对器官系统的发育尤其有害。6、7因此，预防这些不良影响需要采取一种方法来解决怀孕早期的饮酒行为。由于许多女性可能要到第六周才能确认怀孕，只有当我们在怀孕前发现并干预最有可能接触酒精的妇女时，才能获得最大的预防益处。
FETAL ALCOHOL SYNDROME (FAS) is regarded as one of the leading preventable causes of mental retardation in the United States. 1 Although FAS is found primarily among children whose mothers were chronic, heavy alcohol consumers during pregnancy, 2 ongoing research has documented a spectrum of adverse reproductive, infant, and child health outcomes resulting from prenatal alcohol exposure, some starting at thresholds as low as four drinks per week. 3, 4 Although surveys show that 9 of 10 women are aware of the adverse reproductive health consequences of drinking during pregnancy, 1 in 1995 approximately 175,000 pregnancies were exposed to levels of alcohol known to carry increased risk for adverse pregnancy and infant outcomes. 5 The adverse effects of prenatal alcohol exposure extend throughout pregnancy but are particularly deleterious to developing organ systems during the early part of the first trimester. 6, 7 Therefore, prevention of these adverse effects requires an approach that addresses alcohol use behaviors during the early weeks of pregnancy. As pregnancy recognition may not occur until the sixth week in many women, the maximum prevention benefit can be gained only if we find and intervene with women at greatest risk for an alcoholexposed pregnancy before they become pregnant.