RFLPs in human X-linked PGK1: a new probe for the PstI RFLP demonstrates strong linkage disequilibrium with the BgII RFLP.
RFLPs in human X-linked PGK1: a new probe for the PstI RFLP demonstrates strong linkage disequilibrium with the BgII RFLP.
复制标题
人 X 连锁 PGK1 中的 RFLP：PstI RFLP 的新探针表现出与 BgII RFLP 的强烈连锁不平衡。
DOI：
10.1093/nar/17.18.7551
复制
发表时间：
1989
影响因子：
14.9
通讯作者：
Puck,JM
中科院分区：
文献类型：
--
作者：
Smead,DL;Nussbaum,RL;Puck,JM
INTRODUCTION: Several RFLP's have been described in the human phosphoglycerate kinase 1 (PGK1) gene in Xql3. Whereas the PstI polymorphism as detected with PGK1 cDNA (Hutz et al.) was complicated by multiple X-linked and autosomal constant bands, only two bands are seen with a fourth-intron genomic probe. We have compared this PstI RFLP to the 5'BglI RFLP detected by pSPT-PGK (Vogelstein et al.) and have found them to be in strong linkage disequilibrium.
