Validity of a New Kit Measuring Salivary Lactate Dehydrogenase Level for Screening Gingivitis.
Validity of a New Kit Measuring Salivary Lactate Dehydrogenase Level for Screening Gingivitis.
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DOI：
10.1155/2017/9547956
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
Morita M
中科院分区：
文献类型：
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作者：
Ekuni D;Yamane-Takeuchi M;Kataoka K;Yokoi A;Taniguchi-Tabata A;Mizuno H;Miyai H;Uchida Y;Fukuhara D;Sugiura Y;Tomofuji T;Morita M
瞄准本研究的目的是确定一种新的试剂盒，可以评估唾液乳酸脱氢酶（LD）水平在真实的时间筛查牙龈炎的有用性。材料和方法。本研究纳入了70例全身健康志愿者[29例男性和41例女性;平均年龄± SD：24.1 ± 2.6岁]。从每个参与者收集静息唾液，并使用试剂盒（具有1至10的整数标度的变色片）对LD水平进行真实的评估。牙医测量了所有牙齿上六个部位的探诊袋深度、临床附着水平和探诊出血部位的比例（% BOP）。当BOP值≥ 20%时诊断为牙龈炎。结果Logistic回归模型显示唾液LD水平与平均% BOP呈正相关（比值比：1.47，95%可信区间：1.132-1.916，P < 0.001）。以LD水平为8.0为临界值，该试剂盒的敏感性和特异性分别为0.89和0.98。结论.唾液LD水平的新试剂盒测量可能是一个有用的工具，以筛选牙龈炎的年轻人，这有助于早期发现未来的牙周炎。
Aim. The aim of this study was to determine the usefulness of a new kit that can evaluate salivary lactate dehydrogenase (LD) level in real time for screening gingivitis. Materials and Methods. The study included 70 systemic healthy volunteers [29 males and 41 females; mean age ± SD: 24.1 ± 2.6 years]. Resting saliva was collected from each participant and LD level was evaluated in real time using the kit (a color-changing sheet with an integer scale ranging from 1 to 10). A dentist measured probing pocket depth, clinical attachment level, and the proportion of sites with bleeding on probing (% BOP) at six sites on all teeth. Gingivitis was diagnosed when the BOP value was ≥20%. Results. Salivary LD level was positively correlated with mean % BOP (odds ratio: 1.47, 95% confidence interval: 1.132–1.916, and P < 0.001) in a logistic regression model. The sensitivity and specificity of the kit were 0.89 and 0.98, respectively, at a cut-off value of 8.0 for LD level. Conclusions. The new kit for measurement of salivary LD level may be a useful tool to screen for gingivitis in young adults, which contributes to early detection of future periodontitis.