Association between cognitive impairment and cardiovascular burden in patients with severe mental disorder

Association between cognitive impairment and cardiovascular burden in patients with severe mental disorder
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DOI:
10.1080/13546805.2019.1676709
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发表时间:
2019-10-11
影响因子:
1.7
通讯作者:
Munoz Prados, Jordina
Munoz Prados, Jordina
中科院分区:
医学4区
文献类型:
--
作者:
Foguet-Boreu, Quinti;Guardia Sancho, Anna;Munoz Prados, Jordina

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Introduction: Cognitive impairment is related to an increase in cardiovascular risk (CVR) in the general population. However, in severe mental disorder (SMD), the evidence is less consistent. Few studies have evaluated the relationship between cognition and vascular burden in SMD. This study determines the relationship between cognition and vascular burden in patients with SMD. Methods: Sixty SMD patients (61% men, mean age: 46) attending a psychosocial rehabilitation centre were included. We evaluated sociodemographic, clinical, laboratory, quality of life and functionality characteristics. And we analysed the association between cognitive performance and vascular burden. Results: SMD diagnoses were: 41.7% schizophrenia, 20.0% bipolar, 5.0% schizoaffective, 21.7% depressive and 11.7% other. Cognitive impairment was present in 55% of the cases. The average vascular burden was 3.2. Patients with cognitive impairment have a significantly higher vascular burden than patients without cognitive impairment (p?