Variability in the region downstream of the blaCMY-2 β-lactamase gene in eschetichia coli and Salmonella enterica plasmids

Variability in the region downstream of the blaCMY-2 β-lactamase gene in eschetichia coli and Salmonella enterica plasmids
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DOI:
10.1128/aac.50.4.1590-1593.2006
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发表时间:
2006-04-01
影响因子:
4.9
通讯作者:
Call, DR
Call, DR
中科院分区:
医学2区
文献类型:
--
作者:
Kang, MS;Besser, TE;Call, DR

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我们用测序和聚合酶链式反应的方法研究了大肠杆菌和肠沙门氏菌的质粒携带的blA(CMY-2)β-内酰胺酶基因两侧的区域。结果显示BLA下游区域(CMY-2)存在遗传异质性,并确定了一个可能的转座元件BLA(CMY-2)。
We used sequencing and PCR mapping to investigate the regions flanking the bla(CMY-2) P-lactamase gene carried by plasmids from Escherichia coli and Salmonella enterica. Results revealed genetic heterogeneity in the region downstream from bla(CMY-2) and identified a putative transposable element bearingbla(CMY-2).