Maternal control of suspensor programmed cell death via gibberellin signaling
Maternal control of suspensor programmed cell death via gibberellin signaling
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母体通过赤霉素信号控制悬柄程序性细胞死亡
DOI：
10.1038/s41467-019-11476-3
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发表时间：
2019-08-02
影响因子：
16.6
通讯作者：
Sun, Meng-Xiang
中科院分区：
文献类型：
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作者：
Shi, Ce;Luo, Pan;Sun, Meng-Xiang
植物胚胎的产生和发育是在一个被母体组织包围的稳定且保护良好的微环境中进行的，这对胚胎的发生至关重要。然而，负责母体组织到原胚胎通信的信号机制尚不清楚。在这里，我们报告了母体组织到原胚胎交流的途径。我们发现了一种DELLA蛋白NtCRF1 (ntcy调节因子1)，它调节悬架程序性细胞死亡（PCD）。NtCRF1可以结合到ntcys2的启动子上，并响应赤霉素（gibberellin， GA）调控悬浮子pcd -开关模块NtCYS-NtCP14。我们证实了GA4作为触发悬索PCD的主要信号，是通过母体组织中ntga3oxs的瞬时激活在微柱内皮中产生的。因此，我们提出GA是一种母体到原胚胎的通信信号，该信号在原胚胎中通过GID1-CRF1-CYS-CP14信号级联解码。利用这种交流模式，母体组织精确地控制胚胎胚柄PCD，并能够以阶段依赖的方式哺育原胚胎。
Plant embryos are generated and develop in a stable and well-protected microenvironment surrounded by maternal tissue, which is vital for embryogenesis. However, the signaling mechanisms responsible for maternal tissue-to-proembryo communication are not well understood. Here, we report a pathway for maternal tissue-to-proembryo communication. We identify a DELLA protein, NtCRF1 (NtCYSregulative factor 1), which regulates suspensor programmed cell death (PCD). NtCRF1 can bind to the promoter ofNtCYSand regulate the suspensor PCD-switch module NtCYS-NtCP14 in response to gibberellin (GA). We confirm that GA4, as a primary signal triggering suspensor PCD, is generated in the micropylar endothelium by the transient activation ofNtGA3oxsin the maternal tissue. Thus, we propose that GA is a maternal-to-proembryo communication signal that is decoded in the proembryo by a GID1-CRF1-CYS-CP14 signaling cascade. Using this mode of communication, maternal tissue precisely controls the embryonic suspensor PCD and is able to nurse the proembryo in a stage-dependent manner.