En bloc resection of colon carcinoma adherent to other organs: An efficacious treatment?

En bloc resection of colon carcinoma adherent to other organs: An efficacious treatment?
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整块切除粘附于其他器官的结肠癌:有效的治疗方法吗?

DOI:
10.1007/bf02051070
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发表时间:
1991
影响因子:
3.9
通讯作者:
J. Jeekel
J. Jeekel
中科院分区:
医学2区
文献类型:
--
作者:
H. Kroneman;A. Castelein;J. Jeekel

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1977年至1984年,对56例结直肠癌伴其他脏器癌行手术治疗。23例(41%)接受了姑息治疗,未进行切除。本组平均生存期6个月。在33例(59%)结肠癌和邻近器官肿瘤生长的患者中评价了整块切除术的结果。病理分期基于Dukes(Astler和Coller)分类。Dukes' B癌15例。14名患者为Dukes' C,4名患者为Dukes' D。4年生存率如下:Dukes' B,47%; Dukes' C,29%; Dukes' D,0%。整个组的4年生存率为33%。术后并发症和死亡率分别为6%和3%。累及邻近结构的结肠癌不应被视为不可治愈的Dukes' D癌;整块切除是适用的,并且可以在可接受的发病率和死亡率下进行。
: From 1977 to 1984, 56 patients with colon cancer adherent to other organs were operated upon. Twenty-three (41 percent) underwent palliative treatment without resection. The mean survival in this group was 6 months. The results of en bloc resection were evaluated in 33 patients (59 percent) with colon carcinoma and tumor growth in adjacent organs. Pathologic staging was based on Dukes'(Astler and Coller) classification. Dukes' B carcinoma was shown in 15 patients. Dukes' C in 14 patients, and Dukes' D in four patients. The 4-year survival rate was as follows: Dukes' B, 47 percent; Dukes' C, 29 percent; and Dukes' D, 0 percent. The 4-year survival rate for the whole group was 33 percent. The postoperative morbidity and mortality were 6 percent and 3 percent, respectively. Colon cancer with involvement of adjacent structures should not be regarded as an incurable Dukes' D carcinoma; en bloc resection is indicated and can be performed with acceptable morbidity and mortality.