The possible clinical utility of the alcohol biomarker phosphatidylethanol for managing suspected alcohol withdrawal in hospitalized patients: A case report.
The possible clinical utility of the alcohol biomarker phosphatidylethanol for managing suspected alcohol withdrawal in hospitalized patients: A case report.
复制标题
酒精生物标志物磷脂酰乙醇在治疗住院患者疑似酒精戒断方面的可能临床效用：病例报告。
DOI：
10.1111/ajad.13516
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发表时间：
2024
期刊：
影响因子：
--
通讯作者：
Suzuki,Joji
中科院分区：
文献类型：
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作者：
Edinoff,AmberN;Hathaway,DavidB;MartinezGarza,David;Rosen,JordanH;Suzuki,Joji
背景和目的酒精戒断是否开始药物治疗的决定通常是基于对自我报告的酒精使用和戒断症状的检查。磷脂酰乙醇（PEth）是一种生物标志物，可以在临床决策的目标在withdrawal management.MethodsThis报告介绍了三个案件突出的潜在临床效用的PEth在照顾个人的风险酒精withdrawals.ResultsTwo的情况下接受苯巴比妥时，他们的PEth显示，风险的撤药是低的，一个情况下，PEth可以显示这是必要的。结果只能在延迟的方式，但是，可能是有用的通知临床护理。讨论和结论PEth可以是一个有用的工具，如果没有延迟。PEth可用于快速排除酒精戒断，避免误诊和延长住院时间。科学意义这是一项临床病例研究，可用于观察住院患者的PEth和戒断。它建议PEth可以作为一种快速排除酒精戒断的方法，以避免误诊和延长住院时间的可能性。
Background and ObjectivesThe decision to initiate pharmacotherapy for alcohol withdrawal is typically based on examining self‐reported use of alcohol and symptoms of withdrawal. Phosphatidylethanol (PEth) is a biomarker that could aim in clinical decision‐making in withdrawal management.MethodsThis report describes three cases highlighting the potential clinical utility of PEth in caring for individuals at risk for alcohol withdrawal.ResultsTwo of the cases received phenobarbital when their PEth showed that the risk of withdrawal was low and one case where PEth could have shown this was needed. The results were only available in a delayed fashion, however, could have been useful in informing clinical care.Discussion and ConclusionPEth can be a useful tool if available without delay. PEth can be used to quickly rule out alcohol withdrawal and avoid misdiagnoses and prolonged hospital stays.Scientific SignificanceThis is a clinical case study available looking at PEth and withdrawal in hospitalized patients. It proposes that PEth can be used as a way to quickly rule out alcohol withdrawal to avoid misdiagnoses and the possibility of a prolonged hospital stay.