MODULATION OF HEAT PAIN PERCEPTION BY HIGH-FREQUENCY TRANSCUTANEOUS ELECTRICAL NERVE-STIMULATION (TENS)

MODULATION OF HEAT PAIN PERCEPTION BY HIGH-FREQUENCY TRANSCUTANEOUS ELECTRICAL NERVE-STIMULATION (TENS)
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DOI:
10.1097/00002508-199106000-00008
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发表时间:
1991-01-01
影响因子:
2.9
通讯作者:
DUNCAN, GH
DUNCAN, GH
中科院分区:
医学2区
文献类型:
--
作者:
MARCHAND, S;BUSHNELL, MC;DUNCAN, GH

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虽然许多研究表明,高频无痛经皮电神经刺激(TENS)减少临床疼痛,控制研究的调制实验疼痛的TENS产生了矛盾的结果。 本研究评估了高频无痛TENS对热痛感知的影响,使用的模型,我们以前已经证明是敏感的其他非药物镇痛治疗。 我们发现,TENS显著降低了受试者对疼痛和近疼痛热刺激(43-51 ℃)的评分(p = 0.01),并将疼痛阈值从46.7提高到47.9 ℃(p = 0.002)。 安慰剂刺激对受试者的评分或疼痛阈值没有影响。 此外,TENS并没有改变受试者对视觉刺激的评级,表明镇痛效果不是由于非特异性分心。 这些数据表明,TENS改变了实验产生的自然疼痛刺激的感知。 TENS相关的调制也似乎是由其他非药物镇痛操作,如反刺激和注意力的变化产生的。
Although many studies have indicated that high frequency nonpainful transcutaneous electrical nerve stimulation (TENS) reduces clinical pain, controlled studies of the modulation of experimental pain by TENS have produced conflicting results. This study evaluated the effect of high frequency nonpainful TENS on heat pain perception using a model that we have previously shown to be sensitive to other nonpharmacological analgesic treatments. We found that TENS significantly reduced subjects' ratings of painful and near painful heat stimuli (43-51-degrees-C) (p = 0.01) and increased the pain threshold from 46.7 to 47.9-degrees-C (p = 0.002). Placebo stimulation had no effect on the subject's ratings or on their pain thresholds. Furthermore, TENS did not alter subjects' ratings of visual stimuli, indicating that the analgesic effect was not due to a nonspecific distraction. These data suggest that TENS alters the perception of experimentally produced natural pain stimuli. The TENS related modulation also appears to be comparable to that produced by other nonpharmacological analgesic manipulations such as counterirritation and changes in attention.