MUSCLE GLYCOGEN-SYNTHESIS AFTER EXERCISE - EFFECT OF TIME OF CARBOHYDRATE INGESTION
MUSCLE GLYCOGEN-SYNTHESIS AFTER EXERCISE - EFFECT OF TIME OF CARBOHYDRATE INGESTION
复制标题
DOI：
10.1152/jappl.1988.64.4.1480
复制
发表时间：
1988-04-01
影响因子：
3.3
通讯作者：
COYLE, EF
中科院分区：
文献类型：
--
作者：
IVY, JL;KATZ, AL;COYLE, EF
研究了运动后摄入碳水化合物补充剂的时间对肌糖原储备的影响。12名男性骑自行车者在自行车测力计上以68%VO2max连续运动70分钟，在2个不同的场合以88%VO2max的6个2分钟间隔中断。运动后立即（P-EX）或运动后2小时（2 P-EX）摄入25%碳水化合物溶液（2 g/kg体重）。在运动后0、2和4 h，从股外侧肌采集肌肉活检。在运动前和运动中以及运动后的特定时间从肘前静脉采集血样。运动后即刻的肌糖原对于P-EX和2 P-EX治疗没有显著差异。在运动后的第一个2小时期间，肌糖原储存的速率为7.7 μ mol·cm-1。g湿重-1·cnt·dot. h-1，但仅为2.5 μ mol. g湿重-1·cnt·dot. h-1的2 P-EX处理。在恢复的第二个2小时期间，糖原储存的速率减慢至4.3 μ mol·cm-1。g湿重-2·cm·dot. h-1，但增加到4.1 μ mol·cm-1。g湿重-1·cnt·dot. h-1处理2 P-EX.然而，在恢复的前2 h内，该速率仍比P-EX处理的速率慢45%（P < 0.05）。尽管血浆葡萄糖和胰岛素水平显著升高，但糖原储存的速度较慢。结果表明，运动后延迟摄入碳水化合物补充剂将导致肌糖原储存率降低。
The time of ingestion of a carbohydrate supplement on muscle glycogen storage postexercise was examined. Twelve male cyclists exercised continuously for 70 min on a cycle ergometer at 68% .ovrhdot.VO2max, interrupted by six 2-min intervals at 88% .ovrhdot.VO2max on 2 separate occasions. A 25% carbohydrate solution (2 g/kg body wt) was ingested immediately postexercise (P-EX) or 2 h postexercise (2P-EX). Muscle biopsies were taken from the vastus lateralis at 0, 2, and 4 h postexercise. Blood samples were obtained from an antecubital vein before and during exercise and at specific times after exercise. Muscle glycogen immediately postexercise was not significantly different for the P-EX and 2P-EX treatments. During the first 2 h postexercise, the rate of muscle glycogen storage was 7.7 .mu.mol .cntdot. g wet wt-1 .cntdot. h-1 for the P-EX treatment, but only 2.5 .mu.mol .cntdot. g wet wt-1 .cntdot. h-1 for the 2P-EX treatment. During the second 2 h of recovery, the rate of glycogen storage slowed to 4.3 .mu.mol .cntdot. g wet wt-2 .cntdot. h-1 during treatment P-EX but increased to 4.1 .mu.mol .cntdot. g wet wt-1 .cntdot. h-1 during treatment 2P-EX. This rate, however, was still 45% slower (P < 0.05) than that for the P-EX treatment during the first 2 h of recovery. This slower rate of glycogen storage occurred despite significantly elevated plasma glucose and insulin levels. The results suggest that delaying the ingestion of a carbohydrate supplement postexercise will result in a reduced rate of muscle glycogen storage.