Enhancing nucleophilicity in ionic liquid [bmim]HSO4: A recyclable media and catalyst for the halogenation of alcohols
Enhancing nucleophilicity in ionic liquid [bmim]HSO4: A recyclable media and catalyst for the halogenation of alcohols
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DOI：
10.1016/j.molcata.2008.11.040
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发表时间：
2009-04
影响因子：
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通讯作者：
N. Gupta;G. L. Kad;Jasvinder A. Singh
中科院分区：
文献类型：
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作者：
N. Gupta;G. L. Kad;Jasvinder A. Singh
Bronsted酸性离子液体1-丁基-3-甲基咪唑硫酸氢[bmim] hso4已被证明是一种有效的可重复使用的催化剂和溶剂，用于芳香和脂肪醇的卤化，并与微波和热加热相结合。利用微波能不仅加快了反应速度，而且提高了产率。此外，无水离子液体有利于卤化物离子对醇的亲核攻击，从而表明醇的亲核特性增强。离子液体易于制备、收率高、易于再生，进一步扩大了该方法的应用范围。
Bronsted acidic ionic liquid 1-butyl-3-methylimidazolium hydrogen sulphate [bmim]HSO4has been demonstrated as an efficient reusable catalyst and solvent, for halogenation of aromatic and aliphatic alcohols in conjunction with microwave and thermal heating. Use of microwave energy not only accelerates the reaction rate, but also provides enhanced yields. Moreover, anhydrous ionic liquid facilitates nucleophilic attack of halide ions on alcohols, thus indicating the enhancement in their nucleophilic character. Easy work up, good yields and facile regeneration of the ionic liquid further increases the scope of the developed methodology.