Precancerous lesions of the colon and rectum. Classification and controversial issues.

Precancerous lesions of the colon and rectum. Classification and controversial issues.
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结肠和直肠的癌前病变。

DOI:
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发表时间:
1962
期刊:
Journal of the American Medical Association (JAMA)
影响因子:
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通讯作者:
B. Morson
B. Morson
中科院分区:
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文献类型:
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作者:
B. Morson

文献摘要

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人们呼吁在使用“息肉”一词时要更加精确,不幸的是,“息肉”一词越来越多地被用作“腺瘤”的同义词。“良性肠息肉有许多不同的病理类型。这里提出的分类强调只有腺瘤、乳头状腺瘤和绒毛状乳头状瘤是癌前息肉。不同组织学类型的肠息肉之间的区别进行了讨论,特别是参考腺瘤的结肠和直肠在儿童和青年人和错构瘤组的息肉,包括Peutz-Jeghers和青少年类型。与溃疡性结肠炎癌的病理描述和解释提供了这些不寻常的病理表现。强调了对每一位溃疡性结肠炎患者进行无限期仔细随访的价值。
A plea is made for greater precision in the use of the word "polyp," which has, unfortunately, become increasingly used as synonymous with "adenoma." There are many different pathological varieties of benign intestinal polyp. The classification here presented emphasizes that the only precancerous polyps are the adenoma, papillary adenoma, and villous papilloma. The distinction between the different histological types of intestinal polyp is discussed with particular reference to adenomas of the colon and rectum in children and young adults and the hamartomatous group of polyps including the Peutz-Jeghers and juvenile types. The pathology of carcinoma in association with ulcerative colitis is described and an explanation offered for these unusual pathological appearances. The value of a careful follow-up of every patient with ulcerative colitis for an indefinite period of time is emphasized.