INSERTION OF A D-GLUCOSAMINE RESIDUE INTO THE ALPHA-CYCLODEXTRIN SKELETON - A MODEL SYNTHESIS OF CHIMERA CYCLODEXTRINS
INSERTION OF A D-GLUCOSAMINE RESIDUE INTO THE ALPHA-CYCLODEXTRIN SKELETON - A MODEL SYNTHESIS OF CHIMERA CYCLODEXTRINS
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DOI：
10.1039/c39910000289
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发表时间：
1991-03-01
影响因子：
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通讯作者：
KUZUHARA, H
中科院分区：
文献类型：
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作者：
SAKAIRI, N;WANG, LX;KUZUHARA, H
通过一个糖苷键的乙酰分解裂变，包括与2-叠氮基-2-脱氧-D-吡喃葡萄糖衍生物偶联、再环化和最终后处理（催化氢解等）在内的一系列操作，将α-环糊精过乙酸酯2有效转化为二十二碳-O-乙酰基麦芽六糖3，得到含有D-葡萄糖胺残基作为单糖的新型β-环糊精类似物10组件。
Efficient conversion of alpha-cyclodextrin peracetate 2 into icosa-O-acetylmaltohexaose 3 by acetolytic fission of one glycosidic linkage, a series of manipulations including coupling with a 2-azido-2-deoxy-D-glucopyranose derivative, recyclization and final work-up (catalytic hydrogenolysis etc.) gave a novel beta-cyclodextrin analogue 10 containing a D-glucosamine residue as a monosaccharide component.