Sleep spindles provide indirect support to the consolidation of emotional encoding contexts
Sleep spindles provide indirect support to the consolidation of emotional encoding contexts
复制标题
DOI：
10.1016/j.neuropsychologia.2014.09.016
复制
发表时间：
2014-10-01
期刊：
影响因子：
2.6
通讯作者：
Lewis, Penelope A.
中科院分区：
文献类型：
--
作者：
Cairney, Scott A.;Durrant, Simon J.;Lewis, Penelope A.
在依赖睡眠的巩固过程中，情绪记忆往往会先于中性记忆得到加强。然而，在最近的研究中，我们发现，当情绪与记忆的情境特征而不是其中心结构有关时，情况并非如此，这表明情绪情境受到睡眠的独特属性的影响。因此，我们检查了支持情绪背景表征的睡眠特定机制，并询问这些机制是否与中枢情绪记忆处理中已经涉及的机制有所不同，例如快速眼动睡眠（REM）。参与者对中性前景图像进行编码，每个图像都与情绪消极或中性背景（上下文）图像相关联。对前景/背景图像关联的情绪的立即和延迟测试由 4 小时的巩固期分开，该巩固期包括完全清醒或包括 2 小时的多导睡眠监测小睡。尽管消极情境的记忆与快速眼动睡眠或任何其他睡眠参数无关，但睡眠纺锤波（12-15 Hz）预测中性情境的遗忘会增加，反应时间会减慢。结合之前将纺锤体与情绪记忆处理联系起来的工作，我们的数据可能表明纺锤体为睡眠中的情感显着记忆提供多层支持，这种影响的性质取决于这些记忆的情绪是否与其中心或情境特征有关。因此，虽然纺锤体可能会介导中央情感信息的直接强化，如先前的工作所建议的，但它们也可能通过抑制不显着的中性背景来同时为情感背景提供间接支持。 (C) 2014 年，爱思唯尔有限公司出版。
Emotional memories tend to be strengthened ahead of neutral memories during sleep-dependent consolidation. In recent work, however, we found that this is not the case when emotion pertains to the contextual features of a memory instead of its central constructs, suggesting that emotional contexts are influenced by distinct properties of sleep. We therefore examined the sleep-specific mechanisms supporting representations of emotional context and asked whether these differ to those already implicated in central emotional memory processing, such as rapid eye movement sleep (REM). Participants encoded neutral foreground images that were each associated with an emotionally negative or neutral background (context) image. Immediate and delayed tests for the emotionality of the foreground/background image association were separated by a 4-h consolidation period, which consisted of either total wakefulness or included a 2-h polysomnographically monitored nap. Although memory for negative contexts was not associated with REM, or any other parameter of sleep, sleep spindles (12-15 Hz) predicted increased forgetting and slowed response times for neutral contexts. Together with prior work linking spindles to emotional memory processing, our data may suggest that spindles provide multi-layered support to emotionally salient memories in sleep, with the nature of such effects depending on whether the emotionality of these memories pertains to their central or contextual features. Therefore, whereas spindles may mediate a direct strengthening of central emotional information, as suggested in prior work, they may also provide concurrent indirect support to emotional contexts by working to suppress non-salient neutral contexts. (C) 2014 Published by Elsevier Ltd.