Baseline characteristics and outcomes of COVID-19 patients admitted to a Respiratory Intensive Care Unit (RICU) in Southern Italy.
Baseline characteristics and outcomes of COVID-19 patients admitted to a Respiratory Intensive Care Unit (RICU) in Southern Italy.
复制标题
DOI：
10.4081/mrm.2020.704
复制
发表时间：
2020-01-28
影响因子：
2.3
通讯作者：
Resta O
中科院分区：
文献类型：
--
作者：
Di Lecce V;Carpagnano GE;Pierucci P;Quaranta VN;Barratta F;Zito A;Buonamico E;Resta O
最近的新型冠状病毒病（COVID-19）大流行，首先在中国，然后也在意大利，引起了人们对重症监护病房（ICU）饱和问题的关注。几乎所有的既往报道都显示，在ICU中，只有不到一半的患者接受有创机械通气（IMV）治疗，其余患者接受无创呼吸支持。这突出了呼吸重症监护病房（RICU）的作用，在那里，中度至重度呼吸衰竭患者可以接受无创呼吸支持治疗，避免入住ICU。在本报告中，我们描述了2020年3月11日至5月31日期间在巴里Policlinico RICU收治的97例因COVID-19导致的中度至重度呼吸衰竭患者的基线特征和临床结局。在我们的人群中，大多数受试者为男性（72%）、非吸烟者（76%），平均年龄为69.65±14岁。91%的患者至少有一种合并症，60%的患者有两种以上的合并症。入院时，40%的患者显示PaO 2/FiO 2比值在100 - 200之间，17%的患者显示PaO 2/FiO 2比值<100。入院时平均Pa 02/FiO 2比值为186.4±80。这些患者接受了无创呼吸支持治疗，40%采用CPAP，38%采用BPAP，3%采用HFNC，11%采用标准氧疗或通过气管切开术使用IMV（从ICU降级的患者，8%）。51%的患者出院后转入普通病房（GW），30%的患者转入ICU，死亡19%。据我们所知，这是为数不多的在ICU外（RICU）治疗的COVID-19呼吸衰竭患者的描述经历之一。与其他在ICU接受无创呼吸支持治疗的患者的经验相比，我们患者的结局令人满意，其特征在于疾病进展的几个风险因素。在艾德和ICU之间的RICU的战略性分配可能对我们患者的临床结局产生积极影响。
The recent Coronavirus disease 19 (COVID-19) pandemic, first in China and then also in Italy, brought to the attention the problem of the saturation of Intensive Care Units (ICUs). Almost all previous reports showed that in ICU less than half of patients were treated with invasive mechanical ventilation (IMV) and the rest of them with non-invasive respiratory support. This highlighted the role of respiratory intensive care units (RICUs), where patients with moderate to severe respiratory failure can be treated with non-invasive respiratory support, avoiding ICU admission. In this report, we describe baseline characteristics and clinical outcomes of 97 patients with moderate to severe respiratory failure due to COVID-19 admitted to the RICU of the Policlinico of Bari from March 11th to May 31st 2020. In our population, most of the subjects were male (72%), non-smokers (76%), with a mean age of 69.65±14 years. Ninety-one percent of patients presented at least one comorbidity and 60% had more than two comorbidities. At admission, 40% of patients showed PaO2/FiO2 ratio between 100 and 200 and 17% showed Pa02/FiO2 ratio <100. Mean Pa02/FiO2 ratio at admission was 186.4±80. These patients were treated with non-invasive respiratory support 40% with CPAP, 38% with BPAP, 3% with HFNC, 11% with standard oxygen therapy or with IMV through tracheostomy (patients in step down from ICU, 8%). Patients discharged to general ward (GW) were 51%, 30% were transferred to ICU and 19% died. To the best of our knowledge, this is one of the few described experiences of patients with respiratory failure due to COVID-19 treated outside the ICU, in a RICU. Outcomes of our patients, characterized by several risk factors for disease progression, were satisfactory compared with other experiences regarding patients treated with non-invasive respiratory support in ICU. The strategical allocation of our RICU, between ED and ICU, might have positively influenced clinical outcomes of our patients.
登录
查看更多内容
影响因子：
168.9
作者：
Huang, Chaolin;Wang, Yeming;Cao, Bin
通讯作者：
Cao, Bin
影响因子：
11.8
作者：
Ji, Dong;Zhang, Dawei;Qin, Enqiang
通讯作者：
Qin, Enqiang
DOI：
10.1183/16000617.0287-2020
发表时间：
2020-09-30
期刊：
European respiratory review : an official journal of the European Respiratory Society
影响因子：
--
作者：
Bai C;Chotirmall SH;Rello J;Alba GA;Ginns LC;Krishnan JA;Rogers R;Bendstrup E;Burgel PR;Chalmers JD;Chua A;Crothers KA;Duggal A;Kim YW;Laffey JG;Luna CM;Niederman MS;Raghu G;Ramirez JA;Riera J;Roca O;Tamae-Kakazu M;Torres A;Watkins RR;Barrecheguren M;Belliato M;Chami HA;Chen R;Cortes-Puentes GA;Delacruz C;Hayes MM;Heunks LMA;Holets SR;Hough CL;Jagpal S;Jeon K;Johkoh T;Lee MM;Liebler J;McElvaney GN;Moskowitz A;Oeckler RA;Ojanguren I;O'Regan A;Pletz MW;Rhee CK;Schultz MJ;Storti E;Strange C;Thomson CC;Torriani FJ;Wang X;Wuyts W;Xu T;Yang D;Zhang Z;Wilson KC
通讯作者：
Wilson KC
影响因子：
9.8
作者：
Higgs, A.;McGrath, B. A.;Cook, T. M.
通讯作者：
Cook, T. M.
中国武汉市 138 例 2019 新型冠状病毒感染肺炎住院患者的临床特征。
影响因子：
120.7
作者：
Wang, Dawei;Hu, Bo;Peng, Zhiyong
通讯作者：
Peng, Zhiyong