Synthesis of a bis-amino acid that creates a sharp turn.
Synthesis of a bis-amino acid that creates a sharp turn.
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合成产生急转弯的双氨基酸。
DOI：
10.1021/ol048585f
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Schafmeister,ChristianE
中科院分区：
文献类型：
--
作者：
Habay,StephenA;Schafmeister,ChristianE
报道了一种新的双氨基酸1的合成方法。该单体被设计成在组装成低聚物时产生紧密弯曲的结构。该单体被证明耦合到先前开发的monomer2通过对酰胺键，以创建一个强烈弯曲的螺梯低聚物。在水溶液中用二维核磁共振法测定了齐聚物3的结构。
The synthesis of a new bis-amino acid1is presented. This monomer is designed to create a tightly curved structure when assembled into oligomers. The monomer is demonstrated to couple to the previously developed monomer2through pairs of amide bonds to create a strongly bent spiro-ladder oligomer. The structure of oligomer3was determined in aqueous solution using two-dimensional NMR.