Description of the predictors of persistent post-concussion symptoms and disability after mild traumatic brain injury: the SHEFBIT cohort.
Description of the predictors of persistent post-concussion symptoms and disability after mild traumatic brain injury: the SHEFBIT cohort.
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DOI：
10.1080/02688697.2019.1598542
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发表时间：
2019-08-01
影响因子：
1.1
通讯作者：
Singh, Rajiv
中科院分区：
文献类型：
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作者：
Booker, James;Sinha, Saurabh;Singh, Rajiv
简介：一些患有轻度创伤性脑损伤（mTBI）的患者会出现持续性脑震荡后症状（PPCS）和长期残疾。目前mTBI的预后模型有很大的无法解释的方差，这限制了它们在临床环境中的使用。目的：本研究旨在确定与PPCS和长期残疾相关的背景人口统计学和mTBI细节。研究方法：作为研究的一部分，分析了急诊科（艾德）中来自谢菲尔德创伤后脑损伤（SHEFBIT）队列的mTBI患者。PPCS和长期残疾分别使用Rivermead脑震荡后问卷和Rivermead损伤后随访问卷进行测量，在后续脑损伤诊所。结果：招募了647名患者的代表性mTBI样本，随访率为89%。未参加者年龄较大（p < 0.001），退休比例较大（p < 0.001），合并症负担较大（p = 0.009）。多因素分析表明，女性、既往精神病史、GCS
Introduction: Several patients who suffer Mild Traumatic Brain Injury (mTBI) develop Persistent Post-Concussion Symptoms (PPCS) and long-term disability. Current prognostic models for mTBI have a large unexplained variance, which limits their use in a clinical setting. Aim: This study aimed to identify background demographics and mTBI details that are associated with PPCS and long-term disability. Methods: Patients from the SHEFfield Brain Injury after Trauma (SHEFBIT) cohort with mTBI in the Emergency Department (ED) were analysed as part of the study. PPCS and long-term disability were measured using the Rivermead Post-Concussion Questionnaire and the Rivermead Post-Injury Follow-up Questionnaire respectively, during follow up brain injury clinics. Results: A representative mTBI sample of 647 patients was recruited with a follow-up rate of 89%. Non-attenders were older (p < 0.001), a greater proportion were retired (p < 0.001) and had a greater burden of comorbidity (p = 0.009). Multivariate analysis identified that female gender, previous psychiatric history, GCS