SEQUENTIAL AND AVERAGE ATTRIBUTABLE FRACTIONS AS AIDS IN THE SELECTION OF PREVENTIVE STRATEGIES

SEQUENTIAL AND AVERAGE ATTRIBUTABLE FRACTIONS AS AIDS IN THE SELECTION OF PREVENTIVE STRATEGIES
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DOI:
10.1016/0895-4356(94)00161-i
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发表时间:
1995-05-01
影响因子:
7.2
通讯作者:
GEFELLER, O
GEFELLER, O
中科院分区:
医学2区
文献类型:
--
作者:
EIDE, GE;GEFELLER, O

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在过去的十年中,基于二分反应的多变量模型估计可归因分数的方法得到了广泛的发展。这些方法提供了计算一组暴露变量的总可归因分数的方法,这些暴露变量可能针对一组混杂变量进行了调整。本文概述了一种逐步计算可归属分数的方法。目的是研究预防几种暴露对疾病风险的影响,一次一种,以不同的顺序。该程序引入了序贯和平均归因分数的概念,作为将疾病风险归因于不同暴露的辅助手段。的程序和概念说明了一些常见的肺部疾病症状的患病率的横断面研究的数据分析。
Methods for estimating the attributable fraction based on a multivariate model for a dichotomous response have been extensively developed in the last decade. These methods provide the means for calculating the total attributable fraction for a set of exposure variables possibly adjusted for a set of confounding variables. In this paper, a procedure for stepwise calculation of attributable fractions is outlined. The purpose is to study the effect on risk of disease of preventing several exposures, one at a time, in different orderings. This procedure introduces the concepts of sequential and average attributable fractions as aids for attributing the risk of disease to different exposures. The procedure and concepts are illustrated by analyzing data from a cross-sectional study on the prevalence of some frequent symptoms of lung disease.