Numerical design and experimental hydraulic testing of an axial flow ventricular assist device for infants and children
Numerical design and experimental hydraulic testing of an axial flow ventricular assist device for infants and children
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DOI：
10.1097/mat.0b013e31815581ea
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发表时间：
2007-11-01
期刊：
影响因子：
4.2
通讯作者：
Olsen, Don B.
中科院分区：
文献类型：
--
作者：
Throckmorton, Amy L.;Untaroiu, Alexandrina;Olsen, Don B.
在美国，婴儿和儿童的机械循环支持选择非常有限。现有的循环支持系统已被证明是成功的短期儿科援助，但并不完全成功的桥梁移植或桥梁恢复。为了解决替代儿科机械辅助的这一实质性需求，我们正在开发一种新型磁悬浮轴流式儿科心室辅助装置（PVAD），用于长期心室支持。三个主要的数值设计和优化阶段已经完成。基于最新的数值设计（PVAD 3）建造了一个原型，并在流动回路中进行了液压测试。塑料PVAD原型输送0.5 - 4 Ipm，在6，000 - 9，000 rpm的运行速度下产生50 - 115 mm Hg的压力上升。实验测试数据和数值预测相关性良好。发现这些数据集之间的误差通常为7.8%，在较高流速下的最大偏差为24%。数值模拟的轴向流体力范围为0.5至1 N，偏离实验结果一般为8.5%，在较高的流速下最大偏差为12%。这些水力结果证明了PVAD 3的优异性能，并说明了设计目标的实现。
Mechanical circulatory support options for infants and children are very limited in the United States. Existing circulatory support systems have proven successful for short-term pediatric assist, but are not completely successful as a bridge-to-transplant or bridge-to-recovery. To address this substantial need for alternative pediatric mechanical assist, we are developing a novel, magnetically levitated, axial flow pediatric ventricular assist device (PVAD) intended for longer-term ventricular support. Three major numerical design and optimization phases have been completed. A prototype was built based on the latest numerical design (PVAD3) and hydraulically tested in a flow loop. The plastic PVAD prototype delivered 0.5-4 Ipm, generating pressure rises of 50-115 mm Hg for operating speeds of 6,000-9,000 rpm. The experimental testing data and the numerical predictions correlated well. The error between these sets of data was found to be generally 7.8% with a maximum deviation of 24% at higher flow rates. The axial fluid forces for the numerical simulations ranged from 0.5 to 1 N and deviated from the experimental results by generally 8.5% with a maximum deviation of 12% at higher flow rates. These hydraulic results demonstrate the excellent performance of the PVAD3 and illustrate the achievement of the design objectives.