High incidence of idiopathic nephrotic syndrome in East Asian children: a nationwide survey in Japan (JP-SHINE study)
High incidence of idiopathic nephrotic syndrome in East Asian children: a nationwide survey in Japan (JP-SHINE study)
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DOI：
10.1007/s10157-016-1319-z
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发表时间：
2017-08-01
影响因子：
2.3
通讯作者：
Honda, Masataka
中科院分区：
文献类型：
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作者：
Kikunaga, Kaori;Ishikura, Kenji;Honda, Masataka
背景关于东亚地区特发性肾病综合征(INS)的流行病学情况知之甚少。以前的研究表明INS在亚洲儿童中的发病率较高，但其发病率也有下降的趋势。方法我们对6个月至15岁的日本儿童进行了一项全国性的研究。2010年1月1日至2012年12月31日期间新诊断为INS的儿童符合条件。排除先天性肾病综合征或继发于肾炎的肾病综合征。结果2099例儿童初诊为INS，随访4年。INS的发病率估计为每年6.49例/10万儿童，与地理区域无明显相关性。男女比例为1.9，约50%的儿童是
Background Little is known regarding the epidemiology of idiopathic nephrotic syndrome (INS) in East Asia. Previous studies have suggested higher incidence of INS in Asian children, though decreasing trend of its incidence has also been shown.Methods We conducted a nationwide study of Japanese children aged 6 months to 15 years with INS. Children who were newly diagnosed with INS between 1 January 2010 and 31 December 2012 were eligible. Children with congenital nephrotic syndrome or nephrotic syndrome secondary to nephritis were excluded.Results A total of 2099 children were initially diagnosed with INS and were followed for up to 4 years. The estimated incidence of INS was 6.49 cases/100,000 children per year, without clear correlation with geographical region. The male: female ratio was 1.9 and approximately 50 % of children were