Changes of intracortical inhibition during motor imagery in human subjects
Changes of intracortical inhibition during motor imagery in human subjects
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DOI：
10.1016/s0304-3940(99)00120-2
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发表时间：
1999-03-26
影响因子：
2.5
通讯作者：
Trompetto, C
中科院分区：
文献类型：
--
作者：
Abbruzzese, G;Assini, A;Trompetto, C
采用双脉冲经颅磁刺激，采用条件性测试范式，对正常受试者在连续手指运动心理模拟过程中皮质抑制和易化的变化进行了研究。运动表象时，无论运动诱发电位的绝对大小如何，松弛的拇对掌(OP)肌的皮质抑制(刺激间期为3ms)显著减少。皮质抑制量与OF轻度自愿收缩时观察到的量相似。在12ms的ISI时，没有观察到皮质易化的变化。这些数据支持这样一种假设，即在心理模拟和实际执行运动活动期间，包括初级运动皮质在内的类似神经结构都被激活。(C)1999爱思唯尔爱尔兰科学有限公司。保留所有权利。
Paired-pulse transcranial magnetic stimulation with a conditioning-test paradigm was used to assess changes of corticocortical inhibition and facilitation during mental simulation of sequential finger movements in normal subjects. The cortico-cortical inhibition (at interstimulus interval, ISI, of 3 ms) was significantly reduced in the relaxed opponens pollicis (OP) muscle during motor imagery, regardless of the absolute size of the test motor evoked potential. The amount of cortico-cortical inhibition was similar to that observed during a mild voluntary contraction of the OF. No change of cortico-cortical facilitation was observed at the ISI of 12 ms. The data support the hypothesis that similar neural structures, including the primary motor cortex, are activated during both mental simulation and actual execution of motor activities. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.