Soporific signaling: how flies sleep through the night.

Soporific signaling: how flies sleep through the night.
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催眠信号:苍蝇如何整夜睡觉。

DOI:
10.1038/nn0907-1079
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发表时间:
2007
影响因子:
25
通讯作者:
Colwell,ChristopherS
Colwell,ChristopherS
中科院分区:
医学1区
文献类型:
--
作者:
Colwell,ChristopherS

文献摘要

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黑腹果蝇的睡眠机制已经被研究过,它表现出与脊椎动物睡眠相似的行为。一项新的研究发现,在这种模式下,一种生长因子信号通路参与了睡眠调节和巩固。抑制这一途径会导致一种类似于人类失眠的睡眠模式。
The mechanisms of sleep have been studied inDrosophila melanogaster, which show behaviors reminiscent of sleep in vertebrates. A new study identifies a growth factor signaling pathway involved in sleep regulation and consolidation in this model. Inhibiting this pathway causes a sleep pattern that is similar to insomnia in humans.