Gracile, cuneate, and spinal trigeminal projections to inferior olive in rat and monkey.
Gracile, cuneate, and spinal trigeminal projections to inferior olive in rat and monkey.
复制标题
大鼠和猴子的薄状肌、楔状肌和脊柱三叉神经向下橄榄的投射。
DOI：
10.1002/(sici)1096-9861(19961118)375:3
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Strominger,NL
中科院分区：
文献类型：
--
作者：
Molinari,HH;Schultze,KE;Strominger,NL
在猫，体感核团向下橄榄发出大量的投射，在那里它们以躯体定位的方式终止。尽管猫的下等橄榄的组织被用来解释来自其他物种的数据，但公布的数据表明，这种组织可能并不普遍存在。本研究调查了白化大鼠和食蟹猴的下橄榄是否接受相同的脑干躯体感觉输入，这些输入是否按躯体组织进行组织，如果是，该组织如何与猫的组织进行比较。用辣根过氧化物酶标记麦芽凝集素或生物素化葡聚糖标记三叉神经薄束核、楔核和脊束核的投射。将结果与CATS(Berkley和Hand[1978]J.Comp)的数据进行了比较。神经。大鼠和猴的三叉神经薄束核、楔状核和脊束核都投射到对侧的下橄榄核，在那里每个核都有一个明显的优先终末区域。与猫一样，向内侧副橄榄核和尾侧背副橄榄核的投射并不是以精确组织的方式终止的。然而，投射到吻侧背侧副橄榄核形成了清晰的体视图。这些体感定位图与猫的不同之处在于，三叉神经核的输入被限制在吻部，因此尾端只接受来自薄束核和楔状核的输入。这些数据表明，这三个物种向下橄榄的体感投射具有相似的组织原理。然而，在这一组织的细节方面存在着明显的物种差异。©1996 Wiley-Liss，Inc.
In the cat, somatosensory nuclei send substantial projections to the inferior olive, where they terminate in a somatotopic fashion. Although the organization of the cat inferior olive has been used to interpret data from other species, published data suggest this organization may not occur universally. The present study investigated whether the inferior olive in albino rats and cynomolgus monkeys receives the same brainstem somatosensory inputs, whether these inputs are organized somatotopically and, if so, how the organization compares with that in the cat. Projections from the gracile, cuneate and spinal trigeminal nuclei were labeled with wheat germ agglutinin conjugated to horseradish peroxidase or with biotinylated dextran. The results were compared with data from cats (Berkley and Hand [1978] J. Comp. Neurol. 180:253‐264).In the rat and monkey, the gracile, cuneate and spinal trigeminal nuclei all project to the contralateral inferior olive, where each nucleus has a distinct preferred terminal field. As in the cat, projections to the medial accessory olive and caudal dorsal accessory olive did not terminate in a precisely organized fashion. Projections to the rostral dorsal accessory olive, however, formed a clear somatotopic map. These somatotopic maps differed from those in the cat in that input from the trigeminal nucleus was confined rostrally, so that the caudal end only received input from the gracile and cuneate nuclei.These data indicate that similar organizational principles characterize the somatosensory projections to the inferior olives of the three species. Nevertheless, distinct species differences occur with regard to the details of this organization. © 1996 Wiley‐Liss, Inc.