Interaction of serotonin with vagal- and ACh-induced bronchoconstriction in canine lungs.
Interaction of serotonin with vagal- and ACh-induced bronchoconstriction in canine lungs.
复制标题
血清素与迷走神经和乙酰胆碱诱导的犬肺支气管收缩的相互作用。
DOI：
10.1152/jappl.1982.52.4.964
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Nadel,JA
中科院分区：
文献类型：
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作者：
Sheller,JR;Holtzman,MJ;Skoogh,BE;Nadel,JA
在7只麻醉犬的10个实验中，5-羟色胺气雾剂增强了对两条切断的颈迷走神经外周端电刺激的支气管收缩反应。支气管收缩反应乙酰胆碱（ACh）气雾剂后5-羟色胺不变。我们的结论是，5-羟色胺作用于副交感神经节或节后神经末梢的水平，以加强支气管收缩反应迷走神经刺激。
The bronchoconstrictor response to electrical stimulation of the peripheral ends of both cut cervical vagus nerves was potentiated by serotonin aerosols in 10 experiments in 7 anesthetized dogs. The bronchoconstrictor response to acetylcholine (ACh) aerosols was unchanged after serotonin. We conclude that serotonin acts at the level of the parasympathetic ganglia or the postganglionic nerve terminal to potentiate the bronchoconstrictor response to vagal stimulation.