Assessing health-related quality of life in patients with heart failure: a systematic, standardized comparison of available measures
Assessing health-related quality of life in patients with heart failure: a systematic, standardized comparison of available measures
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DOI：
10.1007/s10741-013-9394-7
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发表时间：
2014-05-01
影响因子：
4.6
通讯作者：
Alonso, Jordi
中科院分区：
文献类型：
--
作者：
Garin, Olatz;Herdman, Michael;Alonso, Jordi
系统评估可用于心力衰竭 (HF) 患者的健康相关生活质量 (HRQL) 工具。通过系统评价确定了七份心力衰竭特异性 HRQL 问卷及其度量属性的相关研究：慢性心力衰竭评估工具、心脏健康状况充血性心力衰竭、慢性心力衰竭问卷 (CHFQ)、堪萨斯城心肌病问卷 (KCCQ)、左心室疾病问卷 (LVDQ)、明尼苏达心力衰竭生活问卷 (MLHFQ) 和严重心力衰竭患者的生活质量问卷。每台仪器均由四位专家使用标准化工具进行评估，用于评估患者报告的结果（EMPRO；分数从 0 到 100）。四份问卷的“概念模型”属性得到了足够的分数（中位数> 50）。 LVDQ 的“可靠性”中位数最高（72.8）。 CHFQ、KCCQ 和 MLHFQ 在“有效性”方面都获得了合理的分数（从 54.4 到 76.4）。评审者将 KCCQ 在“变革敏感性”方面评为最高（中位数 94.4）。只有 CHFQ (50.0) 和 KCCQ (72.2) 在“可解释性”属性上获得了足够的分数。根据 EMPRO 总体得分，评分最高的工具是 KCCQ (64.4) 和 MLHFQ (60.7)，其次是 CHFQ (59.2)。基于对现有 HF 特定 HRQL 问卷的首次系统且可靠的专家评估，证据似乎支持选择 KCCQ、MLHFQ 和 CHFQ 而非其他问卷，这需要对度量属性进行进一步研究。
To systematically evaluate available health-related quality of life (HRQL) instruments for use in patients with heart failure (HF). Seven HF-specific HRQL questionnaires and associated studies of their metric properties were identified by systematic review: the Chronic Heart Failure Assessment Tool, the Cardiac Health Profile congestive heart failure, the Chronic Heart Failure Questionnaire (CHFQ), the Kansas City Cardiomyopathy Questionnaire (KCCQ), the Left Ventricular Disease Questionnaire (LVDQ), the Minnesota Living with Heart Failure Questionnaire (MLHFQ), and the Quality of Life in Severe Heart Failure Questionnaire. Each instrument was assessed by four experts using a standardized tool for evaluating patient-reported outcomes (EMPRO; scores from 0 to 100). Four questionnaires were given adequate scores (median > 50) for the attribute "conceptual model." The LVDQ had the highest rated median for "reliability" (72.8). The CHFQ, the KCCQ, and the MLHFQ all got reasonable scores for "validity" (from 54.4 to 76.4). The reviewers rated the KCCQ the highest in terms of "sensitivity to change" (median 94.4). Only the CHFQ (50.0) and the KCCQ (72.2) received adequate scores for the "interpretability" attribute. The most highly rated instruments based on the overall EMPRO score were the KCCQ (64.4) and the MLHFQ (60.7), followed by the CHFQ (59.2). Based on the first systematic and reliable expert-based evaluation of available HF-specific HRQL questionnaires, the evidence seems to support the choice of the KCCQ, the MLHFQ, and the CHFQ over the others, which require further research on metric properties.