Strategies for recruiting representative samples of Asian Americans for a population-based case-control study.
Strategies for recruiting representative samples of Asian Americans for a population-based case-control study.
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招募亚裔美国人代表性样本进行基于人群的病例对照研究的策略。
DOI：
10.1136/jech-2015-206905
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发表时间：
2016
影响因子：
6.3
通讯作者：
Irwin,Melinda
中科院分区：
文献类型：
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作者：
Wong,CelesteK;Horn-Ross,PamelaL;Gee,GilbertC;Shariff-Marco,Salma;Quach,Thu;Allen,Laura;Bautista,Roxanna;LaChica,PatriciaQuema;Tseng,Winston;Chang,Pancho;Clarke,ChristinaA;Yang,Juan;Le,GemM;Canchola,Alison;Irwin,Melinda
背景 在招募人员（尤其是来自不同种族人群）进行基于人群的研究的有效方法方面，数据有限。本研究的目的是评估使用多种方法确定的对照组之间的变异性和代表性，用于旧金山湾区亚裔美国人、夏威夷原住民和太平洋岛民 (AANHPI) 的乳腺癌病例对照研究。方法我们采用了独特的针对性招募策略组合，包括基于地址的抽样、基于社区的方法以及基于互联网和媒体的方法来招募对照组，根据年龄和种族与基于人群的病例样本进行频率匹配。为了描述参与对照的特征，我们使用 χ2 检验比较了招募来源之间的社会人口统计学特征和癌症风险因素的分布。为了确保我们招募的对照组能够代表潜在的高危人群，我们将对照组的特征（按种族和总体）与加州健康访谈调查 (CHIS) 的数据进行了比较，并根据需要调整了整个研究中招募策略的相对组合，以实现代表性。结果正如预期的那样，通过任何单一方法招募的对照组 (n=483) 都不具有代表性。然而，当跨方法汇总时，对照在很大程度上代表了CHIS所表征的基础来源人群，涉及所研究的特征，包括出生、教育、婚姻状况和体重指数。结论使用有针对性的招募策略的多模式方法是使用单一招募方法来确定基于人群的研究的代表性、多样化对照样本的有效且可行的替代方法。
BackgroundData are limited on effective methods for recruiting persons, especially from ethnically diverse populations, into population-based studies. The goal of this study was to evaluate the variation among and representativeness of controls identified using multiple methods for a population-based case–control study of breast cancer among Asian Americans, Native Hawaiians and Pacific Islanders (AANHPIs) in the San Francisco Bay Area.MethodsWe used a unique combination of targeted recruitment strategies, including address-based sampling, community-based methods, and internet-based and media-based approaches for recruiting controls, frequency matched on age and ethnicity to a population-based sample of cases. To characterise the participating controls, we compared the distribution of sociodemographic characteristics and cancer risk factors between recruitment sources using χ2tests. To ensure that the controls we recruited were representative of the underlying at-risk population, we compared characteristics of the controls, by ethnicity and in aggregate, to data from the California Health Interview Survey (CHIS), and adjusted the relative mix of recruitment strategies throughout the study as needed to achieve representativeness.ResultsAs expected, controls (n=483) recruited by any single method were not representative. However, when aggregated across methods, controls were largely representative of the underlying source population, as characterised by CHIS, with regard to the characteristics under study, including nativity, education, marital status and body mass index.ConclusionsA multimode approach using targeted recruitment strategies is an effective and feasible alternative to using a single recruitment method in identifying a representative, diverse control sample for population-based studies.