SPECIES-DIFFERENCES IN THE DISTRIBUTION OF INFRACUTICULAR F-ACTIN IN OUTER HAIR-CELLS OF THE COCHLEA
SPECIES-DIFFERENCES IN THE DISTRIBUTION OF INFRACUTICULAR F-ACTIN IN OUTER HAIR-CELLS OF THE COCHLEA
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DOI：
10.1016/0378-5955(88)90033-0
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发表时间：
1988-05-01
期刊：
影响因子：
2.8
通讯作者：
THORNE, PR
中科院分区：
文献类型：
--
作者：
CARLISLE, L;ZAJIC, G;THORNE, PR
用四甲基罗丹明鬼笔环肽（F-actin的特异性标记物）研究了几种哺乳动物外毛细胞中丝状肌动蛋白（F-actin）的分布。OHC的静纤毛和表皮板在所有物种的检查（有色豚鼠，连帽大鼠，栗鼠和松鼠猴）含有F-肌动蛋白，然而，一个infracuticular网络的F-肌动蛋白存在于OHC的豚鼠耳蜗的顶端转弯，但不能确定在任何其他物种的检查。
The distribution of filamentous actin (F-actin) in outer hair cells has been examined in several mammalian species using tetramethylrhodamine phalloidin, a specific marker for F-actin. The stereocilia and cuticular plates of the OHC in all species examined (pigmented guinea pig, hooded rat, chinchilla and squirrel monkey) contained F-actin; however, an infracuticular network of F-actin was present in OHC of the apical turns of the guinea pig cochlea but could not be identified in any other species examined.