History and genealogy of the H-2Kb mutants from the C57BL/6Kh colony.
History and genealogy of the H-2Kb mutants from the C57BL/6Kh colony.
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C57BL/6Kh 菌落 H-2Kb 突变体的历史和谱系。
DOI：
10.1007/bf00621950
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发表时间：
1982
期刊：
影响因子：
3.2
通讯作者：
Dunn,GR
中科院分区：
文献类型：
--
作者：
Melvold,RW;Kohn,HI;Dunn,GR
在C57BL/6Kh群体中自发产生的14H-2Kb突变的系谱连同皮肤移植监测和饲养程序的数据一起被提供。14个突变中有8个具有表型和结构上的相似性，但系谱分析和对其同胞和祖先的组织相容性遗传学的评估强烈表明，它们代表了反复发生的突变事件，而不是单个突变在整个群体中的分离。
The genealogy of 14H-2Kbmutations arising spontaneously in the C57BL/6Kh colony is presented together with data from skin-graft monitoring and husbandry procedures. Eight of the 14 mutations have phenotypic and structural similarities, but the pedigree analysis and evaluation of the histocompatibility genetics of their sibs and ancestors strongly indicate that they represent recurring mutational events rather than the segregation of a single mutation throughout the colony.