Antiadhesion Function between a Biological Surface and a Metallic Device Interface at High Temperature by Wettability Control
Antiadhesion Function between a Biological Surface and a Metallic Device Interface at High Temperature by Wettability Control
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DOI：
10.1021/acsbiomaterials.8b00387
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发表时间：
2018-05-01
影响因子：
5.8
通讯作者：
Shiratori, Seimei
中科院分区：
文献类型：
--
作者：
Park, Jun-Yong;Tenjimbayashi, Mizuki;Shiratori, Seimei
在手术过程中，医生使用的各种医疗设备主要由金属材料制成。双极钳用于电外科手术，尤其是神经外科手术。双极钳用于切割、接种和快速电止血。由于双极尖端达到高温，因此与尖端接触的组织和附近的组织会受到损坏。此外，由于组织粘附在双极尖端上，需要清洗或更换设备，因此操作会被延迟。在这里，我们通过在双极镊子上涂上超疏水材料来设计具有抗粘连特性的双极镊子。我们使用双极镊子在不同的组织样本和目标区域比较了达到不同表面温度的涂层效果。此外，还研究了表面润湿性的影响。温度测量和粘附力测量表明，样品的涂层显着限制了温度升高并降低了粘附力。我们证明抗粘附性能取决于疏水材料涂层表面张力的变化。这些涂层有望减少金属装置上的组织粘附并减少对组织的附带热损伤。
During operations, medical doctors use various medical equipment that is mainly manufactured from metallic materials. Bipolar forceps are used for electrosurgery, especially neurosurgery. Bipolar forceps are utilized for cutting, inosculation, and quick hemostasis with electricity. Because bipolar tips reach a high temperature, the tissue that makes contact with the tips and nearby tissue is damaged. In addition, operations are delayed because of the need to wash or change equipment because of tissue adhering to the bipolar tips. Herein, we designed bipolar forceps with antiadhesion properties by coating them with a superhydrophobic material. We compared the effect of the coating by using bipolar forceps in different tissue samples and target areas, which reached different surface temperatures. Furthermore, the effect of the surface wettability was investigated. The temperature measurements and adhesion force measurements indicated that coating of the sample significantly limited the temperature increase and reduced the adhesion force. We demonstrated that the antiadhesion properties depended on the change in the surface tension of the hydrophobic material coating. These coatings are promising for decreasing tissue adhesion on metallic devices and decreasing collateral heat damage to the tissue.