Colors in atypical nevi: a computer description reproducing clinical assessment
Colors in atypical nevi: a computer description reproducing clinical assessment
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DOI：
10.1111/j.1600-0846.2005.00097.x
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发表时间：
2005-02-01
影响因子：
2.2
通讯作者：
Grana, C
中科院分区：
文献类型：
--
作者：
Seidenari, S;Pellacani, G;Grana, C
背景/目的：非典型痣（AN）与早期黑素瘤（MM）有一些皮肤镜特征相似，对数字图像进行计算机处理可能对诊断有帮助，可自动评估非典型痣的颜色，并将数据与明确的良性痣（BN）和黑素瘤的数据进行比较。
方法：使用一种能够对黑素细胞性病变的颜色区域进行数值描述的图像分析程序，对459张视频显微镜图像进行分析，这些图像涉及76个非典型痣、288个明确的良性痣和95个黑素瘤。
结果：黑色、白色和蓝灰色在非典型痣中比在明确的良性痣中更常见，但比在黑素瘤中少见。三组之间的颜色区域值有显著差异。
结论：基于对不同病变类型中不同颜色区域的外观和分布的数学描述，对数值数据进行临床形态学解释可能有助于非典型痣的特征描述以及将其与黑素瘤区分开来。
Background/purpose: Atypical nevi (AN) share some dermoscopic features with early melanoma (MM), and computer elaboration of digital images could represent a useful support to diagnosis to assess automatically colors in AN, and to compare the data with those referring to clearly benign nevi (BN) and MMs.Methods: An image analysis program enabling the numerical description of color areas in melanocytic lesions was used on 459 videomicroscopic images, referring to 76 AN, 288 clearly BN and 95 MMs.Results: Black, white and blue-gray were more frequently found in AN than in clearly BN, but less frequently than in MMs. Color area values significantly differed between the three groups.Conclusion: The clinical-morphological interpretation of the numerical data, based on the mathematical description of the aspect and distribution of different color areas in different lesion types may contribute to the characterization of AN and their distinction from MMs.