Theoretical and experimental model to describe the injection of a polymethylmethacrylate cement into a porous structure
Theoretical and experimental model to describe the injection of a polymethylmethacrylate cement into a porous structure
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DOI：
10.1016/s0142-9612(03)00086-3
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发表时间：
2003-07-01
期刊：
影响因子：
14
通讯作者：
Heini, P
中科院分区：
文献类型：
--
作者：
Bohner, M;Gasser, B;Heini, P
采用一种理论方法来确定聚甲基丙烯酸甲酯骨水泥注入多孔结构后的分布情况。然后将该模型的预测结果与将聚甲基丙烯酸甲酯骨水泥注入开孔陶瓷过滤器所获得的实验结果进行比较。目的是定义一个模型，该模型能够预测哪些因素影响骨水泥渗出的风险，从而了解如何将骨水泥渗出的风险降至最低。计算基于两个重要的流变学定律：哈根 - 泊肃叶定律和达西定律。哈根 - 泊肃叶定律描述了流体在圆柱形管道中的流动。达西定律描述了流体通过多孔介质的流动。该模型预测，当骨水泥粘度、骨孔隙大小、骨渗透率和骨孔隙率增加，以及渗出通道的直径和骨髓粘度降低时，渗出风险会降低。在实验中，可以证明骨髓粘度和渗出通道的影响。因此，该模型被认为是对实验行为的一种恰当近似。总之，实验结果表明该模型是合适的，并且降低渗出风险的最佳实际方法是增加骨水泥的粘度。（C）2003爱思唯尔科学有限公司。保留所有权利。
A theoretical approach was used to determine the distribution of a poly(methylmethacrylate) cement after its injection into a porous structure. The predictions of the model were then compared to experimental results obtained by injecting a polymethylmethacrylate cement into an open-porous ceramic filter. The goal was to define a model that could predict what factors affect the risk of cement extravasation and hence how the risk of cement extravasation can be minimized. The calculations were based on two important rheological laws: the law of Hagen-Poiseuille and the law of Darcy. The law of Hagen-Poiseuille describes the flow of a fluid in a cylindrical tube. The law of Darcy describes the flow of a fluid through a porous media. The model predicted that the extravasation risk was decreased when the cement viscosity, the bone pore size, the bone permeability and the bone porosity were increased, and when the diameter of the extravasation path and the viscosity of the marrow were decreased, Experimentally, the effect of the marrow viscosity and extravasation path could be evidenced. Therefore, the model was believed to be an adequate approximation of the experimental behavior. In conclusion, the experimental results demonstrated that the model was adequate and that the best practical way to decrease the risk of extravasation is to increase the cement viscosity. (C) 2003 Elsevier Science Ltd. All rights reserved.