Recovery of Visuospatial Neglect Subtypes and Relationship to Functional Outcome Six Months After Stroke.
Recovery of Visuospatial Neglect Subtypes and Relationship to Functional Outcome Six Months After Stroke.
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中风后六个月后，视觉空间忽略亚型和与功能结果的关系。
DOI：
10.1177/15459683211032977
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发表时间：
2021-09
影响因子：
4.2
通讯作者：
Demeyere N
中科院分区：
文献类型：
--
作者：
Moore MJ;Vancleef K;Riddoch MJ;Gillebert CR;Demeyere N
背景/目的。本研究旨在探讨复杂的视觉空间忽视行为表型如何预测长期结果，包括卒中后6个月的忽视恢复和更广泛的功能结果。方法.本研究对400名完成牛津认知筛查取消任务的卒中幸存者的急性期和6个月随访数据进行了二次队列研究。在随访时，患者还完成了卒中影响量表问卷。分析这些数据，以确定忽视症状的任何特定组合是否更有可能导致长期忽视或更高程度的功能障碍，从而实现更有针对性的康复。结果总体而言，98/142例（69%）忽视病例在随访时恢复，自我中心/他中心（X2 [1] = 0.66和P = 0.418）或左/右忽视（X2 [2] = 0.781和P = 0.677）的持续性无显著差异。自我中心忽视被发现遵循比例恢复模式，所有患者表现出类似的改善水平随着时间的推移。相反，allocentric忽视遵循非比例恢复模式与慢性忽视患者表现出较慢的速度比那些谁恢复的改善。多元回归分析显示，急性非自我中心性忽视损害的初始严重程度是长期功能预后不良的重要预测因素（F [9，300] = 4.742，P <0.001，校正R2 = 0.098）。结论.我们的研究结果要求对卒中后的自我中心和他中心忽视进行系统的神经心理学评估，因为这些情况的发生和严重程度可能有助于预测卒中严重程度以上的恢复结果。
Background/Objective. This study aims to investigate how complex visuospatial neglect behavioural phenotypes predict long-term outcomes, both in terms of neglect recovery and broader functional outcomes after 6 months post-stroke. Methods. This study presents a secondary cohort study of acute and 6-month follow-up data from 400 stroke survivors who completed the Oxford Cognitive Screen’s Cancellation Task. At follow-up, patients also completed the Stroke Impact Scale questionnaire. These data were analysed to identify whether any specific combination of neglect symptoms is more likely to result in long-lasting neglect or higher levels of functional impairment, therefore warranting more targeted rehabilitation. Results. Overall, 98/142 (69%) neglect cases recovered by follow-up, and there was no significant difference in the persistence of egocentric/allocentric (X2 [1] = .66 and P = .418) or left/right neglect (X2 [2] = .781 and P = .677). Egocentric neglect was found to follow a proportional recovery pattern with all patients demonstrating a similar level of improvement over time. Conversely, allocentric neglect followed a non-proportional recovery pattern with chronic neglect patients exhibiting a slower rate of improvement than those who recovered. A multiple regression analysis revealed that the initial severity of acute allocentric, but not egocentric, neglect impairment acted as a significant predictor of poor long-term functional outcomes (F [9,300] = 4.742, P < .001 and adjusted R2 = .098). Conclusions. Our findings call for systematic neuropsychological assessment of both egocentric and allocentric neglect following stroke, as the occurrence and severity of these conditions may help predict recovery outcomes over and above stroke severity alone.
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影响因子：
2.4
作者：
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通讯作者：
Humphreys, Glyn W.
影响因子：
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