Neck Circumference as an Anthropometric Indicator of Central Obesity in Patients with Prediabetes: A Cross-Sectional Study
Neck Circumference as an Anthropometric Indicator of Central Obesity in Patients with Prediabetes: A Cross-Sectional Study
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DOI：
10.1155/2019/4808541
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发表时间：
2019-01-01
影响因子：
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通讯作者：
Thakkinstian, Ammarin
中科院分区：
文献类型：
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作者：
Anothaisintawee, Thunyarat;Sansanayudh, Nakarin;Thakkinstian, Ammarin
腰围的测量具有很大的变异性和一些局限性，而颈围是一种简单可靠的人体测量指标。本研究旨在评估颈围和腰围之间的关系，并确定颈围的最佳临界值，可以预测糖尿病前期患者的中心性肥胖。这项横断面研究纳入了患有前驱糖尿病的成年患者，定义为空腹血糖水平范围为100 - 125 mg/dL或HbA 1c范围为5.7 - 6.49%，这些患者于2014年10月至2016年3月期间在泰国Ramathibodi医院家庭医学部门诊就诊。从垂直于颈部长轴的喉结正下方水平测量颈围。中心性肥胖的定义是男性和女性的腰围测量值分别大于90和80厘米。采用两两相关系数法探讨颈围与腰围的相关性。进行受试者工作特征（ROC）曲线分析，计算约登指数（Youden index），即敏感性-（1-特异性）。将产生最大约登指数的颈围确定为预测中心性肥胖的最佳截止点。共有1，534名患者符合本研究的条件。调整协变量后，发现颈围与腰围在女性和男性中均显著相关，相关系数分别为1.01（95%CI：0.83，1.20）和0.65（95%CI：0.46，0.85）。经ROC曲线分析，确定女性颈围32 cm和男性颈围38 cm为预测中心性肥胖的最佳临界值。糖尿病前期患者的颈围与腰围密切相关，在筛选中心性肥胖时应考虑颈围作为腰围测量的替代方法。
Measurement of waist circumference has substantial variability and some limitations, while neck circumference is a simple and reliable anthropometric measure. This study aimed to assess the association between neck circumference and waist circumference and to identify the best cutoff of neck circumference that could predict central obesity in prediabetic patients. This cross-sectional study included adult patients with prediabetes, defined as having fasting plasma glucose levels ranging from 100 to 125mg/dL or HbA1c ranging from 5.7 to 6.49%, who visited the outpatient clinic of Family Medicine Department, Ramathibodi Hospital, Thailand, during October 2014 and March 2016. Neck circumference was measured from the level just below the laryngeal prominence perpendicular to the long axis of the neck. Central obesity was defined as having waist circumference measurements greater than 90 and 80cm for males and females, respectively. The correlation between neck circumference and waist circumference was explored by applying pairwise correlation coefficient. Receiver operating characteristic (ROC) curve analysis was performed and Youden index equal to sensitivity - (1-specificity) was calculated. Neck circumference that yielded the maximum Youden index was determined as the optimal cutoff point for prediction of central obesity. There were 1,534 patients eligible for this study. After adjusting for covariables, neck circumference was found to be significantly associated with waist circumference in both females and males, with -coefficients of 1.01 (95% CI: 0.83, 1.20) and 0.65 (95% CI: 0.46, 0.85), respectively. After applying the ROC analysis, neck circumferences 32cm in females and 38cm in males were determined as the best cutoff values to predict central obesity. Neck circumference is strongly correlated with waist circumference in prediabetics and should be considered as an alternative to the waist circumference measurement in screening for central obesity.