Intravenous tissue plasminogen activator for acute ischemic stroke in patients aged 80 years and older - The tPA Stroke Survey Experience
Intravenous tissue plasminogen activator for acute ischemic stroke in patients aged 80 years and older - The tPA Stroke Survey Experience
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DOI：
10.1161/01.str.31.2.370
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发表时间：
2000-02-01
期刊：
影响因子：
8.3
通讯作者：
Levine, SR
中科院分区：
文献类型：
--
作者：
Tanne, D;Gorman, MJ;Levine, SR
背景和目的：在症状发作后3小时内静脉注射组织纤溶酶原激活剂（tPA）是治疗急性缺血性卒中（AIS）的第一种有效方法。然而，很少有数据表明它在老年患者中的应用。我们研究了年龄大于或等于80岁的AIS患者接受tPA治疗的特征、并发症和短期结果。
Background and Purpose-Intravenous tissue plasminogen activator (tPA) administered within 3 hours of symptom onset is the first available effective therapy for acute ischemic stroke (AIS). Few data exist, however, on its use in very elderly patients. We examined the characteristics, complications, and short-term outcome of AIS patients aged greater than or equal to 80 years treated with tPA.Methods-Patients aged greater than or equal to 80 years (n = 30) were compared with counterparts aged