Compliance with contraceptives and other treatments

Compliance with contraceptives and other treatments
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DOI:
10.1016/0029-7844(96)00248-7
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发表时间:
1996-09-01
影响因子:
7.2
通讯作者:
Cramer, JA
Cramer, JA
中科院分区:
医学2区
文献类型:
--
作者:
Cramer, JA

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目的:明确口服避孕药依从性的一些独特问题,并与其他预防和治疗方法进行比较。数据来源:使用了遵守医疗情况的报告,重点是使用微电子监测来评估遵守情况的研究。研究对象包括一般人群和各种人口统计学上不同的群体。研究方法选择:选择29项关于药物依从性的研究(包括调查和具有特定干预措施的临床试验),涉及广泛的医学疾病,与口服避孕药依从性的报告进行比较。制表、整合和结果:避孕方法的依从率很低,但与其他药物治疗的依从率相差不大。可以用几个问题来确定个人是否愿意按照规定使用口服避孕药(例如,是否愿意每天服用一粒药丸,是否愿意返回进行随访,是否愿意报告不良反应)。结论:对各种医学疾病的研究表明,没有任何后果严重到可以假定所有患者都遵守规定的治疗方案。依从性不足往往会降低治疗效果,这表明需要替代方法,而不需要每天依从性。
Objective: To define some of the issues unique to compliance with oral contraceptives, and some comparisons with other preventive and therapeutic treatments.Data Sources: Reports of compliance with medical treatment were used, with a focus on studies using microelectronic monitoring to assess compliance. Studies included the general population and a variety of demographically different groups.Methods of Study Selection: Twenty-nine studies of medication compliance (including surveys and clinical trials with specific interventions), across a broad range of medical disorders, were selected for comparison with reports of oral contraceptive compliance.Tabulation, Integration, and Results: Rates of compliance with contraceptive methods are low, but differ little from rates of compliance with other medical treatments. Several questions might be used to ascertain the likelihood that an individual is willing to use an oral contraceptive as prescribed (eg, willingness to take a daily pill, to return for follow-up, and to report adverse effects).Conclusions: Studies of a variety of medical disorders have shown that no consequence is so severe that all patients can be assumed to comply with the prescribed treatment plan. inadequate compliance often diminishes treatment efficacy, which suggests the need for alternative methods that do not require daily compliance.