A review of aqueous organic reactions for the undergraduate teaching laboratory
A review of aqueous organic reactions for the undergraduate teaching laboratory
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本科教学实验室水相有机反应综述
DOI：
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发表时间：
2009
期刊：
影响因子：
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通讯作者：
A. Dicks
中科院分区：
文献类型：
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作者：
A. Dicks
摘要本文从教育学的角度总结了水中有机反应性的广泛范围。它是针对大学教师的，目的是在学术机构中促进水作为一种溶剂。近年来，水介质中有机反应的研究进展引起了工业界和学术界的广泛关注。现在可以在学生实验室中进行许多例子，包括碳-碳/碳-氮键形成反应和官能团转换(例如，氧化、还原和卤水反应)。实验是从教育文献(期刊文章和实验教科书)中总结出来的，并描述了它们的绿色特征。使用水作为溶剂通常有助于显著提高速率和操作简单性--在有限的实验室时间内培训本科生时，这两点都很重要。此外，还向学生强调了与绿色化学十二原则有关的用水的环境益处。
Abstract This article summarizes the wide scope of aqueous organic reactivity from a pedagogical perspective. It is aimed at university instructors with the goal of promoting water as a solvent in academic institutions. Recently, extensive industrial and scholarly research has concerned development of organic reactions in aqueous media. Many examples are now possible in the student laboratory including carbon–carbon/carbon–nitrogen bond-forming reactions and functional group transformations (e.g. oxidations, reductions, and halohydrations). Experiments are summarized from the educational literature (journal articles and laboratory textbooks) and their green features are described. Using water as solvent often promotes significant rate enhancements and operational simplicity – both of importance when training undergraduates during limited laboratory time. Environmental benefits of using water are additionally highlighted to students’ first hand in relation to the Twelve Principles of Green Chemistry.