Recurrent desmoid tumor of the mediastinum: A case report.

Recurrent desmoid tumor of the mediastinum: A case report.
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DOI:
10.3892/ol.2014.2431
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发表时间:
2014-11
期刊:
影响因子:
2.9
通讯作者:
Wang Y
Wang Y
中科院分区:
医学4区
文献类型:
--
作者:
Xie Y;Xie K;Gou Q;He J;Zhong L;Wang Y

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硬纤维瘤(DT)是一种罕见的良性软组织肿瘤,具有局部浸润的潜力,但不会转移。肿瘤通常以可触及的肿块为特征,但临床病程多变且不可预测。目前的研究提出了一个巨大的纵隔DT表现出肺部受累的情况下。一名50岁女性患者在根治性手术后一年因复发性DT被转诊至华西医院(中国四川成都)。患者随后接受放射治疗。DT起源于纵膈,与通常的表现不同,复发表现为广泛侵犯肺组织,差点被误诊为肺癌脑转移。通过对比增强计算机断层扫描和肿瘤组织学检查诊断肿瘤复发。常规随访显示在入院后9个月没有进一步的肿瘤进展。考虑到不可预测的治疗并发症,可以简单有效地管理复发性DT。“观望”政策可能是治疗这种疾病的可行选择。
Desmoid tumors (DTs) are rare, benign soft-tissue tumors that have the potential for local invasion, but not for metastasis. The tumors are commonly characterized by a palpable mass, but present a variable and unpredictable clinical course. The current study presents the case of a giant mediastinal DT exhibiting lung involvement. A 50-year-old female was referred to the West China Hospital (Chengdu, Sichuan, China) due to a recurrent DT that was identified one year following radical surgery. The patient subsequently received radiation therapy. The DT arose from the mediastinum, unlike the usual presentation, and recurrence presented as extensive invasion into the lung tissue, almost being misdiagnosed as lung cancer with brain metastasis. Tumor recurrence was diagnosed through contrast-enhanced computed tomography and histological examination of the tumor. A routine follow-up revealed no further tumor progression at 9 months post-admission. Taking into account the unpredictable treatment complications, recurrent DTs can be managed simply and efficiently. A ‘wait-and-see’ policy could be a viable therapeutic option for this disease.
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