VALVE AREA AND CARDIAC-OUTPUT IN AORTIC-STENOSIS - QUANTIFICATION BY MAGNETIC-RESONANCE VELOCITY MAPPING
VALVE AREA AND CARDIAC-OUTPUT IN AORTIC-STENOSIS - QUANTIFICATION BY MAGNETIC-RESONANCE VELOCITY MAPPING
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DOI：
10.1016/0002-8703(93)90669-z
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发表时间：
1993-11-01
影响因子：
4.8
通讯作者：
HENRIKSEN, O
中科院分区：
文献类型：
--
作者：
SONDERGAARD, L;HILDEBRANDT, P;HENRIKSEN, O
应用磁共振（MR）速度标测技术对12例主动脉瓣狭窄患者的瓣膜面积和心输出量进行了测定。进行心脏导管插入术、多普勒超声心动图和指示剂稀释以进行比较。仅9例患者可插入左心室导管;在这些病例中，MR测量的平均瓣膜面积为1.2 CM2，而导管数据为0.9 CM2，两种方法之间的平均差异为0.2 CM2。一致性限度为[0.0，+0.5] CM 2，在伴有严重返流的患者中更低。在整个材料中，MR测得的平均面积为1.1 CM2，而多普勒超声心动图数据测得的平均面积为1.2 CM2，平均差异为0.1 CM2和[-0.5，+0.6] CM2作为一致性限度。11例患者的心输出量通过MR定量为平均4.9 L/min，通过指示剂稀释定量为5.0 L/min，平均差异为0.2 L/min，[-0.6，+0.8] L/min作为一致性限值。此外，MR提供了在伴随返流的情况下同时定量促渗剂体积的主要进展。总之，由于主动脉瓣狭窄的两个重要的预后决定因素-瓣膜面积和心输出量-可以量化，MR有可能成为评估主动脉瓣狭窄严重程度的临床工具。
Valve area and cardiac output were determined with magnetic resonance (MR) velocity mapping in 12 patients with aortic stenosis. Heart catherization, Doppler echocardiography, and indicator dilution were performed for comparison. Left ventricle could be catheterized in only nine patients; in these cases, MR measured a mean valve area of 1.2 CM2 compared with 0.9 CM2 derived from catheterization data, with a mean difference of 0.2 CM2 between the 2 methods. The limits of agreement were [0.0, +0.5] CM2, less in patients with an important degree of concomitant regurgitation. In the whole material, MR measured a mean area of 1.1 CM2 compared with 1.2 CM2 derived from Doppler echocardiography data, with a mean difference of 0.1 CM2 and [-0.5, +0.6] CM2 as limits of agreement. In 11 patients the cardiac output was quantified by MR to a mean of 4.9 L/min and by indicator dilution to 5.0 L/min, with a mean difference of 0.2 L/min, and [-0.6, +0.8] L/min as limits of agreement. In addition, MR offers the major advance of simultaneous quantification of regurgitant volume in cases of concomitant regurgitation. In conclusion, because the two important prognostic determinants in aortic stenosis-the valvular area and the cardiac output-may be quantified, MR has potential to become a clinical tool in assessment of severity in aortic stenosis.