SRTR program-specific reports on outcomes: A guide for the new reader
SRTR program-specific reports on outcomes: A guide for the new reader
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DOI：
10.1111/j.1600-6143.2008.02178.x
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发表时间：
2008-01-01
影响因子：
8.8
通讯作者：
Wolfe, R. A.
中科院分区：
文献类型：
--
作者：
Dickinson, D. M.;Arrington, C. J.;Wolfe, R. A.
移植计划和器官采购组织（OPO）之间确实存在结果差异。移植受者科学登记处（SRTR）提供了越来越多的工具来测量和评估移植过程不同阶段的结果。这些工具并不是用来比较两个单独的项目，而是用来帮助识别哪些项目的做法可能需要进一步审查，以避免，纠正或仿效。为了了解哪些结果差异可能是由于服务人群的潜在差异，哪些可能是由于治疗的差异，将结果与“风险调整”的预期值进行比较是很重要的。此外，通过考虑每个估计值的p值或置信区间，认识和评估随机机会在这些结果中可能发挥的作用是很重要的。我们向读者介绍了这些工具的基本解释，以及在阅读SRTR项目特定报告的背景下对它们的解释。我们描述了这些报告的预期受众，包括患者、监测和流程改进机构、付款人和其他人，如媒体。以反映对这些概念及其局限性的基本理解的方式使用这些统计数据对所有受众都有好处。
Differences in outcomes indeed exist among transplant programs and organ procurement organizations (OPO). A growing set of tools are available from the Scientific Registry of Transplant Recipients (SRTR) to measure and assess these outcomes in the different phases of the transplant process. These tools are not intended to compare two individual programs, rather to help identify programs whose practices may need further scrutiny, to be either avoided, corrected or emulated.To understand which differences in outcomes might be due to underlying differences in populations served and which might be due to differences in treatment, it is important to compare outcomes to 'risk-adjusted' expected values. Further, it is important to recognize and assess the role that random chance may play in these outcomes by considering the p-value or confidence interval of each estimate. We present the reader with a basic explanation of these tools and their interpretation in the context of reading the SRTR Program-Specific Reports.We describe the intended audience of these reports, including patients, monitoring and process improvement bodies, payers and others such as the media. Use of these statistics in a way that reflects a basic understanding of these concepts and their limitations is beneficial for all audiences.