Nickel/AlMe(2)Cl-catalysed carbocyanation of alkynes using arylacetonitriles.
Nickel/AlMe(2)Cl-catalysed carbocyanation of alkynes using arylacetonitriles.
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DOI：
10.1039/b907290j
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发表时间：
2009-07
影响因子：
4.9
通讯作者：
A. Yada;Tomoya Yukawa;Y. Nakao;T. Hiyama
中科院分区：
文献类型：
--
作者：
A. Yada;Tomoya Yukawa;Y. Nakao;T. Hiyama
镍/路易斯酸双重催化被发现可以使用芳基乙腈进行炔烃的碳氰化反应，得到一系列三取代的丙烯腈；光学活性α-苯基丙腈的反应表明了一种反应机制，涉及C-CN键的氧化加成并保留其绝对构型。
Nickel/Lewis acid dual catalysis was found to effect the carbocyanation reaction of alkynes using arylacetonitriles, giving a range of triply substituted acrylonitriles; the reaction of optically active alpha-phenylpropionitrile suggested a reaction mechanism that involves oxidative addition of a C-CN bond with retention of its absolute configuration.