The abnormal nucleus as a cause of congenital facial palsy
The abnormal nucleus as a cause of congenital facial palsy
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DOI：
10.1136/adc.83.3.256
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发表时间：
2000-09-01
影响因子：
5.2
通讯作者：
Harrison, DH
中科院分区：
文献类型：
--
作者：
Jemec, B;Grobbelaar, A;Harrison, DH
背景-先天性面瘫（CFP）在临床上定义为出生时出现的面瘫。它与严重的毁容有关，并给受影响的孩子带来功能和情感问题。然而，大多数病例的病因仍然难以捉摸。目的 - 调查神经解剖学异常作为单侧 CFP 原因的作用。方法 - 对 21 名单侧 CFP 患者进行磁共振成像 (MRI) 扫描。 15 名患者仅有单侧 CFP；六名患者患有可能包括单侧 CFP 的综合征。 结果 - 在 15 名仅患有单侧 CFP 的患者中，四名 (27%) 的核异常或 MRI 扫描中该区域的权重异常，而其余 6 名患者中只有一名 (17%)。结论 - 面核本身的发育异常构成了单症状单侧 CFP 的一个重要但以前被忽视的原因。
Background-Congenital facial palsy (CFP) is clinically defined as facial palsy present at birth. It is associated with considerable disfigurement and causes functional and emotional problems for the affected child. The aetiology of the majority of cases however, remains elusive.Aims-To investigate the role of a neuroanatomical abnormality as a cause of unilateral CFP.Methods-Magnetic resonance imaging (MRI) scans were performed on 21 patients with unilateral CFP. Fifteen patients had unilateral CFP only; six suffered from syndromes which can include unilateral CFP.Results-Of the 15 patients with unilateral CFP only, four (27%) had an abnormal nucleus or an abnormal weighting of this area on the MRI scan, compared to one (17%) of the remaining six patients.Conclusion-Developmental abnormalities of the facial nucleus itself constitute an important, and previously ignored, cause of monosymptomatic unilateral CFP.