[Transjugular intrahepatic portasystemic shunt and liver transplantation].
[Transjugular intrahepatic portasystemic shunt and liver transplantation].
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经颈静脉肝内门体分流术与肝移植[J].
DOI：
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发表时间：
1994
期刊：
影响因子：
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通讯作者：
F. Joffre
中科院分区：
文献类型：
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作者：
H. Rousseau;J. Vinel;P. Maquin;B. Suc;I. Bilbao;J. Longo;G. Fourtanier;F. Joffre
在前100例连续接受经颈静脉肝内门体分流术（TIPS）治疗的患者中，12例随后接受了肝移植（TIPS后平均103 +/- 109天）。12例晚期肝硬化（Child B = 5, C = 7）和门静脉高压症患者建立了14个TIPS。7例出现活动性静脉曲张出血或难治性静脉曲张出血，5例出现难治性腹水。分流可以在所有情况下进行。两名患者再次出血（一名在分流梗阻后），并通过插入第二个TIPS成功治疗。对10例进行组织学研究。分流术在所有病例中都是通畅的（除了先前描述的一个病例），腔内表面被结缔组织层和新的内皮覆盖。因此，我们认为这种方法是一种安全有效的治疗门静脉高压症并发症的方法，适用于肝移植患者。
From the first one hundred consecutive patients treated by transjugular intrahepatic portosystemic shunt (TIPS), 12 subsequently underwent liver transplantation (a mean of 103 +/- 109 days after TIPS). Fourteen TIPS were created in 12 patients, with advanced cirrhosis (Child B = 5, C = 7) and portal hypertension. Seven patients presented either active variceal hemorrhage or refractory variceal bleeding, and 5 cases of refractory ascites. The shunt could be performed in all cases. Two patients experienced rebleeding (one after a shunt obstruction) and were successfully treated by insertion of a second TIPS. A histological study was performed in 10 cases. The shunt was patent in all cases (except in one case previously described), and the endoluminal surface was covered by a connective tissue layer and a new endothelium. We therefore conclude that this method is a safe and effective therapy for complications of portal hypertension, in patients referred for liver transplantation.