Persistence of chlamydial infection after treatment for neonatal conjunctivitis.
Persistence of chlamydial infection after treatment for neonatal conjunctivitis.
复制标题
新生儿结膜炎治疗后衣原体感染持续存在。
DOI：
10.1136/adc.56.3.193
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发表时间：
1981
影响因子：
5.2
通讯作者：
N. Lee
中科院分区：
文献类型：
--
作者：
Elisabeth Rees;Anne Tait;D. Hobson;And P KARAYIANNIS;N. Lee
分离阳性衣原体结膜炎患儿咽部感染发生率高。治疗前从23例患儿中分离出12例（52%）的沙眼衣原体，治疗后从4例（12%）的眼睛和14例（41%）的咽中分离出沙眼衣原体。仅外用四环素治疗4周的婴儿中沙眼原体再分离率（75%）明显高于同时外用四环素和口服红霉素治疗2周的婴儿（32%）。与眼睛再次隔离仅与轻微的临床症状相关。由于持续咳嗽，8名婴儿中有2名胸部有炎性病变的影像学征象。这些症状与血清衣原体抗体的高滴度或上升滴度无关。
A high incidence of pharyngeal infection was found in babies with isolation-positive chlamydial conjunctivitis. Chlamydia trachomatis was isolated from the pharynx of 12 (52%) of 23 babies before treatment, and was reisolated from the eyes of 4 (12%) of 34 and from the pharynx of 14 (41%) of 34 after treatment. C trachomatis was reisolated significantly more often from babies treated only with topical tetracycline for 4 weeks (75%) than from those treated with both topical tetracycline and oral erythromycin for 2 weeks (32%). Reisolation from the eyes was associated with only minor clinical signs. Radiological signs of an inflammatory lesion in the chest were found in 2 of 8 babies examined because of persistent cough. These signs were not associated with high or rising titres of serum chlamydial antibody.