A Complementary Pseudo-Resistor with Leakage Current Self-Compensation for Biopotential Amplifiers

A Complementary Pseudo-Resistor with Leakage Current Self-Compensation for Biopotential Amplifiers
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DOI:
10.1109/biocas58349.2023.10389136
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发表时间:
2023-10
期刊:
2023 IEEE Biomedical Circuits and Systems Conference (BioCAS)
影响因子:
--
通讯作者:
Gerald Topalli;Chong Xie;Yingying Fan;Lan Luan;Rongkang Yin;Taiyun Chi
Gerald Topalli;Chong Xie;Yingying Fan;Lan Luan;Rongkang Yin;Taiyun Chi
中科院分区:
其他
文献类型:
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作者:
Gerald Topalli;Chong Xie;Yingying Fan;Lan Luan;Rongkang Yin;Taiyun Chi

文献摘要

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在AC耦合生物电势放大器中使用的常规伪电阻器遭受固有和光致漏电流,这可能使放大器饱和并在放大器输出处引起输入幅度依赖性DC漂移。为了缓解这些问题,本文提出了一种新的互补伪电阻与漏电流自补偿机制。作为概念的证明,使用所提出的伪电阻器的电容反馈生物电位放大器在DB HiTek 180nm CMOS工艺中设计。在测量中,与使用传统伪电阻的放大器相比,它实现了对输入幅度相关的DC漂移和曝光的增强的鲁棒性。它还在使用预先记录的神经信号的体外测试期间证明了高信号保真度。
Conventional pseudo-resistors used in AC-coupled biopotential amplifiers suffer from intrinsic and photo-induced leakage currents, which may saturate the amplifier and induce an input-amplitude-dependent DC drift at the amplifier output. To mitigate these issues, this paper presents a new complementary pseudo-resistor with a leakage current self-compensation mechanism. As proof of concept, a capacitive feedback biopotential amplifier using the proposed pseudo-resistor is designed in the DB HiTek 180nm CMOS process. In the measurement, it achieves enhanced robustness against both input-amplitude-dependent DC drift and light exposure, compared to the amplifier using the conventional pseudo-resistor. It also demonstrates high signal fidelity during in vitro tests using pre-recorded neural signals.