Left ventricular activation imaging by 3-dimensional speckle-tracking echocardiography. Comparison with electrical activation mapping.
Left ventricular activation imaging by 3-dimensional speckle-tracking echocardiography. Comparison with electrical activation mapping.
复制标题
通过 3 维斑点跟踪超声心动图进行左心室激活成像。
作者：
Y. Seo;H. Yamasaki;R. Kawamura;T. Ishizu;Miyako Igarashi;Y. Sekiguchi;H. Tada;K. Aonuma
背景
三维斑点追踪超声心动图（3D-STE）的激活成像旨在可视化从QRS开始的局部收缩开始所需的时间。我们假设激活成像的最佳设置与电激活相关。本研究的目的是确定一个最佳的设置激活成像与3D-STE相比，电压标测系统，并评估这种成像方法的可行性。
方法和结果
我们招募了7名接受电压标测的患者。利用3D-STE的面积变化率（ACR）测量区域变形。在最大ACR值的10%、25%、50%和100%作为局部收缩开始的阈值时获得激活成像数据。通过电压标测的LV电心室内激动时间（IVAT（电））和通过激动成像的机械IVAT（IVAT（机械））的持续时间定义为第一个和最后一个内皮素激动部位之间的时间差。我们在不同的传导模式和起搏配置下获得了21个数据集。在最大ACR值的25%处观察到IVAT（机械）和IVAT（电）之间的最强相关性（IVAT（电）=0.47 * IVAT（机械）+20，R=0.80，P<0.001）。在该设置下，激活成像和电压标测之间的第一个和最后一个激活节段的一致性为90.5%（19项研究）。
结论
3D-STE激活成像可能是一种可行的基于机电耦合的非同步性成像方法。
BACKGROUND
Activation imaging with 3-dimensional speckle-tracking echocardiography (3D-STE) aims to visualize the time required for the onset of regional contraction from QRS onset. We hypothesized that the optimal setting of activation imaging was associated with electrical activation. This study was designed to determine an optimal setting of activation imaging with 3D-STE in comparison with that of a voltage mapping system and to assess the feasibility of this imaging method.
METHODS AND RESULTS
We enrolled 7 patients who underwent electrical voltage mapping. Regional deformation was measured by area change ratio (ACR) with 3D-STE. Activation imaging data were obtained at 10%, 25%, 50%, and 100% of maximal ACR values as the threshold for onset of regional contraction. Duration of LV electrical intraventricular activation time (IVAT(electrical)) by voltage mapping and mechanical IVAT (IVAT(mechanical)) by activation imaging was defined as the time difference between the first and latest endocardial activation sites. We obtained 21 data sets under various conduction patterns and pacing configurations. The strongest correlation between IVAT(mechanical) and IVAT(electrical) was observed at 25% of maximal ACR values (IVAT(electrical)=0.47 * IVAT(mechanical)+20, R=0.80, P<0.001). Concordance of the first and latest activated segments between activation imaging and voltage mapping was 90.5% at this setting (19 studies).
CONCLUSIONS
Activation imaging with 3D-STE may be a feasible noninvasive method of dyssynchrony imaging based on electromechanical coupling.
影响因子：
3.4
作者：
Gurev, V.;Constantino, J.;Trayanova, N. A.
通讯作者：
Trayanova, N. A.