Myocardial strain by Doppler echocardiography - Validation of a new method to quantify regional myocardial function
Myocardial strain by Doppler echocardiography - Validation of a new method to quantify regional myocardial function
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DOI：
10.1161/01.cir.102.10.1158
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发表时间：
2000-09-05
期刊：
影响因子：
37.8
通讯作者：
Smiseth, OA
中科院分区：
文献类型：
--
作者：
Urheim, S;Edvardsen, T;Smiseth, OA
背景-心肌应变是局部变形的量度，根据定义，负应变意味着缩短，正应变意味着伸长。本研究探讨心肌应变是否可以通过多普勒超声心动图测量的时间积分的区域速度梯度，使用sonomicromotry作为参考method.Methods和Results-In 13麻醉犬，心肌纵向应变测量心尖图像的时间积分的区域多普勒速度梯度。将超声节段长度晶体放置在左心室（LV）心尖附近和基底附近。结扎冠状动脉左前降支（LAD）造成心尖部缺血，生理盐水增加前负荷。多普勒测量的收缩期应变百分比与超声测微法测量的应变百分比呈良好的相关性（y=0.82x-1.79，r=0.92，P
Background-Myocardial strain is a measure of regional deformation, and by definition, negative strain means shortening and positive strain, elongation. This study investigates whether myocardial strain can be measured by Doppler echocardiography as the time integral of regional velocity gradients, using sonomicrometry as reference method.Methods and Results-In 13 anesthetized dogs, myocardial longitudinal strain was measured on apical images as the time integral of regional Doppler velocity gradients. Ultrasonic segment-length crystals were placed near the left ventricular (LV) apex and near the base. Apical ischemia was induced by occluding the left anterior descending coronary artery (LAD), and preload was increased by saline. Percentage systolic strain by Doppler correlated well with strain by sonomicrometry (y=0.82x-1.79, r=0.92, P