Motheaten: An Immunodeficient Mouse with Markedly Less Ability to Survive Than the Nude Mouse in a Germfree Environment
Motheaten: An Immunodeficient Mouse with Markedly Less Ability to Survive Than the Nude Mouse in a Germfree Environment
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受害：免疫缺陷小鼠在无菌环境中的生存能力明显低于裸鼠
作者：
Marvin A. Lutzner;Carl T. Hansen
母鼠是一种免疫缺陷突变体，已发现其免疫球蛋白水平升高，表现出自身免疫和早期死亡。由于无菌环境不能提高存活率，似乎是感染以外的某种机制导致了其早期死亡。
The motheaten mouse is an immunodeficient mutant which has been found to have elevated immunoglobulin levels, to exhibit autoimmunity, and early death. Since survival is not improved by a germfree environment, it appears that some mechanism other than infection results in its early demise.